Shyamla Narayan
Download
1 / 42

Presentation PowerPoint File - PowerPoint PPT Presentation


  • 351 Views
  • Updated On :

Shyamla Narayan. Alberto Recio. Ed Overstreet. Andrei Temchin. Burt Evans. Laboratory for Hearing Biology (~1996). Laboratory for Hearing Biology (today). Luis Robles. Jon Siegel. Andrei Temchin. Yun-Hui Fan. Qin Gong. Yi-Bo Fan.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Presentation PowerPoint File' - mike_john


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
Slide1 l.jpg

Shyamla Narayan

Alberto Recio

Ed Overstreet

Andrei Temchin

Burt Evans

Laboratory for Hearing Biology (~1996)


Slide2 l.jpg

Laboratory for

Hearing Biology (today)

Luis Robles

Jon Siegel

Andrei Temchin

Yun-Hui Fan

Qin Gong

Yi-Bo Fan


Slide10 l.jpg

AT THE BASE OF THE COCHLEA, BASILAR-MEMBRANE RESPONSES TO CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

chinchilla

guinea pig

cat


Slide13 l.jpg

COMPRESSIVE NONLINEARITY IN CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

BASILAR-MEMBRANE RESPONSES

TO CLICKS


Slide14 l.jpg

IN SPITE OF THE PROMINENT CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

NONLINEARITIES OF BASILAR-MEMBRANE

VIBRATIONS, THE FOURIER SPECTRA OF

RESPONSES TO CLICKS MATCH, LEVEL

BY LEVEL, THE RESPONSES TO TONES


Slide15 l.jpg

GROWTH OF PEAKS IN RESPONSES TO CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

CLICKS AS A FUNCTION OF STIMULUS

LEVEL


Slide16 l.jpg

COMPRESSIVE NONLINEARITY IS CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

PRESENT WITHIN A SINGLE PERIOD

OF RESPONSE OSCILLATION


Slide17 l.jpg

IN THE CHINCHILLA, BASILAR-MEMBRANE CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

RESPONSES ARE MORE SHARPLY TUNED

AND EXHIBIT GREATER NONLINEARITY

AT THE BASE OF THE COCHLEA THAN AT

THE APEX


Slide27 l.jpg

Compression and other nonlinearities of BM CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

responses probably arise in nonlinear transduction

in outer hair cells

Cooper, 2003


Slide30 l.jpg

RESPONSES OF AUDITORY-NERVE FIBERS CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

EXHIBIT AN INTENSITY-DEPENDENT PHASE

SHIFT THAT IS NOT PRESENT IN BASILAR-

MEMBRANE RESPONSES


Slide31 l.jpg

SECOND-ORDER WIENER KERNELS OF CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

AUDITORY-NERVE FIBERS RESPONSES

TO NOISE


Slide32 l.jpg

FRONT, GROUP AND FILTER DELAYS CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)


Slide33 l.jpg

MAP OF DELAYS FOR CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

THE CHINCHILLA COCHLEA


Slide34 l.jpg

COMPARISON OF GROUP DELAYS OF CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

BASILAR-MEMBRANE VIBRATIONS AND

STIMULUS-FREQUENCY OTOACOUSTIC

EMISSIONS (SFOAEs)


Slide35 l.jpg

BASILA-MEMBRANE RESPONSES AT CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

THE BASE OF THE COCHLEA ARE NOT

MINIMUM-PHASE

Original response Minimum-phase version

(time domain)

44 dB SPL

104 dB SPL


Slide36 l.jpg

BASAL RESPONSES ARE NOT MINIMUM-PHASE CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

44 dB SPL 104 dB SPL

(frequency domain)


Slide37 l.jpg

THE MEASURED PHASE SHIFTS AS A FUNCTION CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

OF GAIN ARE MUCH SMALLER THAN

EXPECTED FROM MINIMUM-PHASE BEHAVIOR


Slide38 l.jpg

EVEN POST-MORTEM RESPONSES CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

ARE NOT MINIMUM-PHASE


Slide39 l.jpg

BASILAR-MEMBRANE RESPONSES AT THE CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

APEX OF THE COCHLEA ARE NOT MINIMUM-PHASE


Slide40 l.jpg

DEVELOPMENT OF BASILAR-MEMBRANE CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

VIBRATIONS IN NEW-BORN GERBILS:

RUDIMENTARY TRAVELING WAVE


Slide41 l.jpg

POST-MORTEM BASILAR-MEMBRANE CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

RESPONSES IN ADULT GERBIL ARE NOT

MINIMUM-PHASE


Slide42 l.jpg

BUT IN-VIVO BASILAR-MEMBRANE RESPONSES CHARACTERISTIC-FREQUENCY TONES GROW AT HIGHLY COMPRESSIVE RATES (e.g., 0.2 dB/dB)

IN IMMATURE COCHLEAE ARE MINIMUM-PHASE


ad