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Synthetic Biology PowerPoint PPT Presentation


Synthetic Biology. 6. Synthetic Biology. What is Synthetic Biology?. Discover Magazine: Scientists of the Year. Undergraduates in Synthetic Bio. international Genetically Engineered Machines. http://parts.mit.edu/registry/index.php/Main_Page. 37 Teams in 2006; 57 in 2007.

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Synthetic Biology

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Synthetic Biology


6


Synthetic Biology


What is Synthetic Biology?


Discover Magazine: Scientists of the Year


Undergraduates in Synthetic Bio.

international Genetically Engineered Machines

http://parts.mit.edu/registry/index.php/Main_Page


37 Teams in 2006; 57 in 2007

http://parts.mit.edu/r/parts/igem/team_list.cgi


Registry of Parts - iGEM Resource

http://parts.mit.edu/registry/index.php/Part_Types


Lego Assembly for DNA Parts

http://parts.mit.edu/registry/index.php/Assembly:Standard_assembly


What can you make in SB?

Self-organized Pattern Formation

Arsenic Detector


Davidson and MWSU Join Forces

2006 iGEM Teams

http://parts2.mit.edu/wiki/index.php/Davidson_2006

http://parts2.mit.edu/wiki/index.php/Missouri_Western_State_University_2006


Burnt Pancake Problem: 2006

Sorting stacks of burnt pancakes

DNA Pancakes: order and orientation


Davidson & Missouri Western: 2006

http://www.bio.davidson.edu/people/kahaynes/FAMU_talk/Living_computer.swf


Modeling Pancake Flipping

-1 2

1 2

1 -2

-1 -2

-2 -1

-2 1

2 1

2 -1

R2: 2 Burnt Pancakes

8 vertices, each with degree 3

Each path taken with probability 1/27


Pancake Graph Theory


Five Prizes in 10 Categories!


MWSU wins Best Presentation!

Five Prizes in 10 Categories!


students

Todd wearsa coat & tie!

Jeff Poet,

Math Prof.

GovernorMatt Blunt

MO Governor Meets MWSU iGEMmers


Hamiltonian Path Problem: 2007


Davidson & Missouri Western: 2007


Split GFP Works!

http://www.bio.davidson.edu/Courses/Immunology/Students/spring2006/Acker/GFP_halfframe.html


Traveling Salesman Problem: 2007


SB Blends Math and Biology

HHMI Proposals Due Fall, 2007


Is SB hard or expensive?

  • Hire rising sophomores

  • Less than $5,000 in lab expenses

  • NSF Undergraduate Biology and Math Program

  • Protocols student-proof and online

  • Creativity and fun encouraged

  • Existing lab equipment and methods

  • Math modeling improves design

  • Fun iGEM competition stimulates students


Hin LVA

Tet

AraC PC

RBS

RBS

pLac

hixC

pBad

hixC

hixC

RE

T

T

T

T

How can SB fit into a curriculum?

  • Seminar course to prepare

  • Research or Independent Study to build

  • Summer research programs

  • Existing Courses: Molecular Biology, Genetics, Cell Biology, Development, Microbiology, Biochemistry, Engineering, Modeling, Lab Methods...


How can we learn more?

  • Attend iGEM 2007 in Boston

  • Read synthetic biology paperswww.bio.davidson.edu/Courses/Synthetic/read.html

  • Familiarize yourself with iGEM wiki

  • Form an iGEM team on your campus

  • Put Synthetic Biology in your HHMI proposal


Is GCAT participating in iGEM?

  • Encouraging PUIs to join the fun

  • Including iGEM in HHMI request

  • Sharing protocols

  • Making List-serve available

  • Synthetic biology workshops possible

  • Develop curriculum and resources to share

http://parts.mit.edu/igem07/index.php/Davidson_Missouri_W


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