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Exercise and CHD. What is cholesterol used for inside the body and how much do we need?. How is cholesterol involved with atherosclerosis?. Injury – HTN, inflammation, infection, trauma, toxic materials, etc. Fatty streak – monocytes form foam cells which become fatty streaks and plaques

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How is cholesterol involved with atherosclerosis l.jpg
How is cholesterol involved with atherosclerosis? we need?

  • Injury – HTN, inflammation, infection, trauma, toxic materials, etc.

  • Fatty streak – monocytes form foam cells which become fatty streaks and plaques

  • Migration and aggregation – macrophages secret growth factors for smooth muscle cells, produce reactive oxygen materials which cause LDL to accumulate

  • Lipid accumulation

  • Maturation of the lesion





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