Cytoskeleton
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CytoSkeleton. By: John Mandziara. Made of. The cytoskeleton is made up of three kinds of filaments: 1. Actin Filaments (Micro) 2. Intermediate Filaments 3. Microtubules . The three parts:. Actin Filaments .

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CytoSkeleton

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Cytoskeleton

CytoSkeleton

By: John Mandziara


Made of

Made of

  • The cytoskeleton is made up of three kinds of filaments:

    1. Actin Filaments (Micro)

    2. Intermediate Filaments

    3. Microtubules


The three parts

The three parts:


Actin filaments

Actin Filaments

  • Monomers of the protein actin polymerize to form long, thin fibers. These are about 8 nm in diameter and, being the thinnest of the cytoskeletal filaments, are also called microfilaments. In skeletal muscle fibers they are called thin filaments

  • What they do:

    1. Provide strength

    2. Start Motion

    3. Interact with myosin (thick) for muscular contractions


Actin

Actin


Intermediate filaments

Intermediate Filaments

  • These cytoplasmic fibers average 10 nm in diameter and thus are "intermediate" in size between actin filaments 8 nm and microtubules 25 nm as well as of the thick filaments of skeletal fibers

  • Types:

    1. Keratins (Hair and Nails)

    2. Lamins (Stabilize the inner membrane)

    3.Nuerofilaments (Strengthen the long axons of neurons)

    4. Vimentins (Provide mechanical strength to muscles)


Intermediate

Intermediate


Microtubules

Microtubules

  • Straight, hollow cylinders whose wall is made up of a ring of 13 "protofilaments"; have a diameter of about 25 nm; are variable in length but can grow 1000 times as long as they are wide; are built by the assembly of dimers of alpha tubulin and beta tubulin; are found in both animal and plant cells.

  • Grow at each end by the polymerization of tubulindimers (powered by the hydrolysis of GTP), and shrink at each end by the release of tubulindimers (depolymerization).

  • Two major groups:

    1. Kinesins (move toward positive end)

    2. Dyneins (move toward negative end)


Microtubules1

Microtubules


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