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PATH Partnerships: Promoting Innovation and Ensuring Impact

This article explores how to ensure that innovations reach vulnerable populations by understanding their needs, creating incentives for technology development, building evidence for decision-making, and strengthening distribution systems. It discusses examples such as the Woman's Condom and Oxytocin in the UniJect Device, and highlights the importance of integrating new innovations into health systems.

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PATH Partnerships: Promoting Innovation and Ensuring Impact

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  1. PATH Partnerships: Promoting Innovation and Ensuring Impact

  2. Ensuring that innovations reach those who need them most. How can we do this?

  3. Four Critical Elements Understand the needs of vulnerable and at-risk populations Create the right incentives for technology development Build the evidence base for informed decision-making Strengthen systems for distribution, delivery, and use

  4. Examples of Recent Innovations Understand the needs of vulnerable and at-risk populations Create the right incentives for technology development Woman’s Condom Build the evidence base for informed decision-making Oxytocin in the Uniject Device Strengthen systems for distribution, delivery, and use Vaccine Vial Monitors

  5. Product Introduction Framework

  6. Woman’s Condom Designed and developed by PATH with input from women and their partners

  7. Woman’s Condom • Need for woman-controlled prevention methods poorly understood by industry and market poorly developed • Public-sector investment and technical leadership essential to drive innovation • Public-private partnership vital for success INNOVATE

  8. Create the right incentives for technology development • Product development partnerships a high-priority investment for donors (PUSH) • Also need financial incentives that harness commercial innovation capacity (e.g., advanced market commitments) (PULL) • Need to strengthen health systems and build markets for sustained commercialization INNOVATE

  9. Oxytocin in the UniJect Device Generate and disseminate evidence for effective postpartum hemorrhage control using oxytocin in the Uniject device

  10. Oxytocin in the Uniject Device • Building the evidence for informed decision-making at international and country level is critical to successful product introduction • Operations research and demonstration projects show the true value of a product • Experience informs choices based on costs and benefits INTRODUCE

  11. Build the evidence base for informed decision-making • Country-led decision-making is crucial • International agency policy and best practice guidelines are essential • Introducing the new products available today creates further incentive for innovation INTRODUCE

  12. Vaccine Vial Monitors Indicator on each vaccine vial that measures heat exposure Allows health workers to discard vials that exceed maximum allowable heat exposure

  13. Vaccine Vial Monitors • Successful integration requires attention to cost and appropriate design • Public policies must be aligned • Patient manufacturing partners are crucial • Value-added product: vaccine producer is the first customer INTEGRATE

  14. Strengthen systems for distribution, delivery, and use • Successful product development and introduction alone will not drive the integration of new innovations within health systems • Policy, financing, human resources, management information systems, procurement and logistics, etc. need specific attention • Only sustained use leads to public health impact INTEGRATE

  15. Ensuring that innovations reach those who need them most Understand the needs of vulnerable and at-risk populations Create the right incentives for technology development Build the evidence base for informed decision-making Strengthen systems for distribution, delivery, and use

  16. Conclusion • Innovative new technologies play an important role in meeting the needs of the most vulnerable • Product development partnerships harness the innovation capacity of the commercial sector • Country engagement is essential, both for ethical testing of new products and decisions about their introduction and use • Support for timely international agency review and endorsement is necessary • Product innovation and introduction must be complemented by policy and financial support for integration into health systems

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