Regional Limbic and Somatosensory Cortical Thinning in Adults with Major Depressive Disorder. Matthew Crawshaw. Theories of MDD. H ypothalamic -pituitary-adrenal (HPA) axis dyfunction
(a) segmentation and smoothed intensities of GM, WM and CSF; (b) thickness measurement results in mm; (c) projection of thickness data onto subject’s surface mesh.
Area of significantly thinner grey matter for MDD patients in the right entorhinal cortex.
Area of significantly thinner grey matter for MDD patients in the left postcentral gyrus. Lowered threshold for cluster size estimation.
SFG = Superior Frontal Gyrus; rMFG = Rostral middle frontal gyrus; cMFG = Caudal middle frontal gyrus; preCG = Precentral gyrus; latOFG = Lateral orbitofrontal gyrus