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George F. White M.D Retired Otolaryngology Student of Wine

George F. White M.D Retired Otolaryngology Student of Wine. Presents: WINE AND HEALTH A comparison of antiquity and modern concepts. Disclaimer #1. Unfortunately ,I have not received funding from any winery or pharmaceutical firm for this presentation. Opus One Winery. Disclaimer #2.

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George F. White M.D Retired Otolaryngology Student of Wine

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  1. George F. White M.DRetired OtolaryngologyStudent of Wine Presents: WINE AND HEALTH A comparison of antiquity and modern concepts

  2. Disclaimer #1 Unfortunately,I have not received funding from any winery or pharmaceutical firm for this presentation Opus One Winery

  3. Disclaimer #2 Any comments regarding religious concepts are based on historical articles and are not intended to represent any personal views on cosmology

  4. Disclaimer # 3 When using the term “myth” the following definition by Dr. Robert Oden, Ph.D. (former Hotchkiss Head Master and President of Kenyon College) is applied:

  5. Disclaimer # 3 Cont. • A myth is a story in narration form with a beginning, middle, and end. • A myth is traditional and social creation within a religious or otherwise distinctive society. • A myth deals with a being who is supernatural and the deeds are impossible for an ordinary human.

  6. Origins of Wine I. Noah Hypothesis • Genesis 1:11 “Every kind of plant that bears seed”

  7. Origins of Wine • Genesis 10:20 “Now Noah, a man of the soil, was the first to plant a vineyard”

  8. Gilgamesh Epic- Search for immortality, Utnapishtim, Mt. Nisir Gilgamesh meets Siduri-Goddess of Wine Origins of Wine

  9. Origin of Wine • Jamshid of the Pishdadian Dynasty • Jamshid’s wife (one of many) and migraine

  10. Origin of Wine • Greek God Zeus and his flood. Oresthens planted the first vineyard

  11. Domestication of Wine NEOLITHIC TIMES Wild Grapes- Diocecious Domestic Grapes-Hermaphroditic

  12. Domestication of Wine St Emilion Rhone Valley Hermitage

  13. The Ancients and Wine Book of Sirach 31:27 “Wine means life for a man if he is moderate in drinking…it was made to make men glad” Zind Humbrecht Robert Mondavi

  14. The Ancients and Wine Dionysos and Hephaistos 550 BC

  15. The Ancients and Wine HOMER Wounds of Philoctetes (Troy) healed with wine by Podaleirius (son of Asclepius)

  16. The Ancients and Wine INDIA Vedic Period (2500 BC) – Gupta Classical (530 AD) Soma-(God of Liquid Pleasure) Rigg-Veda (sacred text) makes the blind see and the lame walk Ayurveda- (Medical text) happiness and good digestion, antidote to fatigue, sorrow , shock, anesthetic Sushruta- (ancient physician) used it as an anesthetic Madya-(wine) classical era; for fatigue, depression and TB if mixed with goat’s milk SOMA

  17. CHINA Wine and black cat liver-malaria Wine and flesh of pit viper- colic, worms, hemorrhoids, flatulence The Ancients and Wine

  18. The Ancients and Wine HIPPOCRATES “Father of Medicine” Cooling fever, diuretic, antiseptic and to help convalescence, jaundice and digestion, menstrual pain

  19. The Ancients and Wine CATO/PLINY Gastric, urologic ailments; snakebite, constipation; calms the soul, nourishes the blood

  20. EARLY CHRISTIANITY • Feast of Cana • Sacrament of the Eucharist

  21. EARLY CHRISTIANITY • St Paul • Timothy 5:23 “Stop drinking only water but have a little wine for the sake of your stomach and your frequent illnesses”

  22. Pre Modern AVICENNA (982-1037) Wine is the best friend of wise people

  23. Pre Modern MAIMONIDES (Jewish) Spain, Egypt 12th Century Wine cures many illnesses, keeps the body healthy

  24. Pre Modern SALERNO MEDICAL SCHOOL Wine raises the tonus, makes the mind lively, hearing sharp and favors with good health RENAISSANCE ENLIGHTENMENT DR. BENJAMIN RUSH-Signer of the Declaration of Independence

  25. Classification Order-Rhamnales Includes IVY ,VA Creeper Family-Vitaceae Genus-Vitis Species-Vinifera • Wild-VV Silvestris • VV Sativa

  26. Structure of a Grape The polyphenols, resveratrol, catechins, quercetin, oligomeric procyanidin and other antioxidants are produced in the skin.

  27. Modern Era MID-20th CENTURY DENIAL Prohibition 1970’s NIH suppressed Framingham Heart study that showed moderate drinkers had 50% fewer deaths from coronary disease than non-drinkers

  28. Modern Era MID-20th CENTURY DENIAL Source: Klatsky, 1981. Annuals of Internal Medicine

  29. Heart Disease Rates in 18 Western Countries Heart Disease Mortality Per 1000 Men Source: St. Leger, The Lancet May 12, 1979 Wine Consumption (4 Oz Glasses/Day)

  30. Modern Era Late 20th Century Denial French Paradox • Dr. Samuel Black 1819 • Dr. Serge Renaud, Bordeaux University • 60 minutes 1991- Morley Safer • Dr. Klatsky-Kaiser Study Cheese Restaurant (Bordeaux)

  31. Modern EraLate 20th Century DenialFrench Paradox • 1999 British Heart Foundation • Rate of Death CHD: • 115/100,000 USA • 83/100,000 France • 2004 WHO-Similar Study Cellar Master, (Rhone Valley)

  32. Formula A simplified concept of how antioxidants work • Cell + oxygen = “free radicals” • Free Radicals + antioxidants = Good Health + 02 = + = Internet Al Hanoi Jane

  33. Modern Era MECHANISM OF ACTION Science of Wine • * The polyphenols inhibit Endothelin I. This compound damages the endothelium and produces vasoconstriction-the primary events for atherosclerosis • Antioxidants in wine prevent the oxidation of LDL which prevents the macrophages from filling up with cholesterol, thus reducing atherosclerosis. • The alcohol itself increases HDL concentration which is anti inflammatory, thus decreases the risk of atherosclerosis • Wine decreases platelet stickiness

  34. Results of Studies CARDIOVASCULAR . • Helps prevent cardiofibrosis. • Dilates small blood vessels, prevents clotting and plaque formation, increases HDL, reduces the risk of stroke and MI. • Moderate consumption of red wine reduces risk factors by 30%-50%.

  35. Results of Findings DIABETES II Reduces risk by 33%-56%, and does not interfere with medication, increases insulin sensitivity “Red wine protects diabetic patients from meal-induced oxidative stress and thrombosis, a pleasant approach to the prevention of cardiovascular disease in diabetes.”

  36. Results of Findings DEMENTIA Moderate drinkers have lower risk of developing dementia and perform better on cognitive tests than non-drinkers.

  37. Results of Findings CANCER Quercetin inhibits growth of cancer and leukemia cells. It potentiates chemotherapy. • 28% lower risks for kidney cancer • Prostate cancer in mice using resveratrol had 87% lower rate • Lung cancer- 22 % less chance Take a deep breathe this will not hurt.

  38. Results of Findings ORTHOPEDICS Hip fractures reduced 39% in elderly. The wine increases estrogen which is protective.

  39. Conclusions THE ANCIENTS WERE CORRECT: • Wine in moderation is good for the health • Exercise • Diet discretion • Excess of alcohol is not healthy • Better yet, select your parents wisely BarrellTasting Grape Harvester

  40. Conclusions WHICH WINES ARE MOST HEALTHY: : • Cabernet Sauvignon • Syrah • Pinot Noir • Ultraviolet Effect WINE WITH FOOD IS BETTER

  41. Appropriate Wine Drinking George, Mark, Sandy Greenbrier

  42. Inappropriate Wine Drinking 3 Bottle Club ? Medical Staff

  43. The End I end with the beginning from Sirach Wine means life for a man if he is moderate in drinking”

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