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临床输血新进展 PowerPoint PPT Presentation


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临床输血新进展. 广东省医学会临床输血分会主委 中国输血协会常务理事 广州血液中心主任医师 江朝富. 临床输血是 WHO 安全输血三大战略之一; 临床输血日益被临床医学家所重视; 临床输血的发展是随着临床医学的发展而发展; 临床输血医学将成为一门独立的边缘学科。. 主要内容. 循证医学在输血中的应用; 细胞治疗进展; 治疗性单采; 临床输血新风险; 血液预警系统; 临床输血的信息管理。. 一、循证医学在输血工作中的应用.

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临床输血新进展

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  • WHO


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1. Evidence-based medicine EBM)


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  • D.L.Sackett


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  • evidence-based transfusion medicine EBTM


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  • EBTMEBTM


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  • 2 EBMrandomizid controlled trials RCT


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1.RCTs

2.Cohort studies

3.Case-control studies

4.Case series

5.Case report

6.Expert opinion

7.Bedside

Observations/

Clinical

expertise


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3


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5


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  • M..F. Murphy


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1Stem cel transplantation HLAHLA-A,HLA-B,HLA-C,HLA-DR,HLA-DQ HLA


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2 Dendritic cells T


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3T Cytotoxic T lymphocytes


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4NK NK cell NK HLA-HLA-


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5Regenerative medicine


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  • C Viswanathan 3115


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  • 6 Gene therapy


Therapeutic apheresis

Therapeutic apheresis


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1 Cascade filtration LDL)


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2 Adsorption techniques


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  • 1DNA


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  • 2-Ig-LDLLDLC1qAFC


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  • 3Complex techniques combined with haemodialysis


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J.P.Isbister


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  • 115R.Y.Dodd


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  • 1Variant Creutzfeldt-Jakob disease v CJD 3vCJD49-690/


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  • 2West Nile Virus WNV

    1999


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  • 20021200710


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  • 3Chikungunya virus CHKV--


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6001RNA


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  • 4Dengue virus DV--


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  • 0%-0.3%


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  • 58Human herpesvirus 8 HHV-8


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  • 0%-0.82%2%-8%

  • HHV-8


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  • 6

    1Babesia 601

    2Malaria


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  • 3SARS ,H5N1


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  • J.P.Isbister

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Heamovigilance system2090


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    1


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  • 4M.Satake

    1JRCB)1993

    220041900

    380%-90%TTI10%-15%80-130


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