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临床输血新进展 PowerPoint PPT Presentation


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临床输血新进展. 广东省医学会临床输血分会主委 中国输血协会常务理事 广州血液中心主任医师 江朝富. 临床输血是 WHO 安全输血三大战略之一; 临床输血日益被临床医学家所重视; 临床输血的发展是随着临床医学的发展而发展; 临床输血医学将成为一门独立的边缘学科。. 主要内容. 循证医学在输血中的应用; 细胞治疗进展; 治疗性单采; 临床输血新风险; 血液预警系统; 临床输血的信息管理。. 一、循证医学在输血工作中的应用.

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临床输血新进展

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  • WHO



1. Evidence-based medicine EBM)


  • D.L.Sackett


  • evidence-based transfusion medicine EBTM


  • EBTMEBTM


  • 2 EBMrandomizid controlled trials RCT


1.RCTs

2.Cohort studies

3.Case-control studies

4.Case series

5.Case report

6.Expert opinion

7.Bedside

Observations/

Clinical

expertise


3


5



  • M..F. Murphy




1Stem cel transplantation HLAHLA-A,HLA-B,HLA-C,HLA-DR,HLA-DQ HLA


2 Dendritic cells T


3T Cytotoxic T lymphocytes


4NK NK cell NK HLA-HLA-


5Regenerative medicine


  • C Viswanathan 3115


  • 6 Gene therapy


Therapeutic apheresis


1 Cascade filtration LDL)



2 Adsorption techniques


  • 1DNA


  • 2-Ig-LDLLDLC1qAFC


  • 3Complex techniques combined with haemodialysis


J.P.Isbister


  • 115R.Y.Dodd


  • 1Variant Creutzfeldt-Jakob disease v CJD 3vCJD49-690/


  • 2West Nile Virus WNV

    1999


  • 20021200710


  • 3Chikungunya virus CHKV--


6001RNA


  • 4Dengue virus DV--


  • 0%-0.3%


  • 58Human herpesvirus 8 HHV-8


  • 0%-0.82%2%-8%

  • HHV-8


  • 6

    1Babesia 601

    2Malaria


  • 3SARS ,H5N1


  • J.P.Isbister

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  • 2

  • 3


  • 4/

  • 5

  • 6

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  • 8

  • 9

  • 10


Heamovigilance system2090


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3


  • 3

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  • 4M.Satake

    1JRCB)1993

    220041900

    380%-90%TTI10%-15%80-130






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