Clinical Trials in IPF. Dr Helen Parfrey. Are clinical trials needed ?. Essential to determine if a drug therapy is beneficial Identify who will benefit the most from the treatment Side effects associated with the drug therapy Information about the disease.
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Dr Helen Parfrey
All patients in the study taking prednisolone and azathioprine
Not compare treatment with N-acetylcysteine alone with placebo
Demedts et al New Engl J Med 2005
Kubo et al, Chest 2005
Noble PW et al, Lancet 2011
Richeldi L et al New Engl J Med 2011
116 studies in IPF
22 therapeutic trials