Receptors
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Receptors. Anatomic Locations for Nausea. Anti-Emetic Medications. 5-HT 3. D 2. M 1 , H 1. GABA. Dimenhydrinate. Receptor types. Receptor types. Receptor types. Scopolamine. Vestibulum. Promethazine. CNS. Prochlorperazine. Area Postrema. Metoclopramide. Click an anatomic location.

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Receptors

Receptors

Anatomic Locations for Nausea

Anti-Emetic Medications

5-HT3

D2

M1, H1

GABA

Dimenhydrinate

Receptor types

Receptor types

Receptor types

Scopolamine

Vestibulum

Promethazine

CNS

Prochlorperazine

Area Postrema

Metoclopramide

Click an anatomic location

GI Tract

Ondansetron

Benzodiazepines

Corticosteroids

Exit

Return to this main screen

X


Receptors

Receptors

Anatomic Locations for Nausea

Anti-Emetic Medications

M1, H1

Dimenhydrinate

Scopolamine

Vestibulum

Promethazine

Dimenhydrinate (Dramamine) is available OTC. The three medications are anticholinergic.

X


Receptors

Receptors

Anatomic Locations for Nausea

Anti-Emetic Medications

5-HT3

D2

M1, H1

GABA

Dimenhydrinate

Scopolamine

Promethazine

CNS

Prochlorperazine

Metoclopramide

Ondansetron

↑ intracranial pressure may require corticosteroid tx. Benzodiazepines may be used for psychiatric causes.

Benzodiazepines

Corticosteroids

X


Receptors

Receptors

Anatomic Locations for Nausea

Anti-Emetic Medications

5-HT3

D2

Prochlorperazine

Area Postrema

Metoclopramide

Ondansetron

Opioid receptors are present in the area postrema, which is located at the base of the 4th ventricle

X


Receptors

Receptors

Anatomic Locations for Nausea

Anti-Emetic Medications

D2

Promethazine

Prochlorperazine

Metoclopramide

GI Tract

Metoclopramide (Reglan) is prokinetic). Promethazine (Phenergan) has more M1/H1-receptor action than D2. Rule out impactions.

X


Anti emetics

Anti-Emetics

From Juan Palacios, MD

Created by Dan Cushman

2010


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