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HEART FAILURE

HEART FAILURE. Jagdish Butany Univ. Toronto & Toronto General Hospital 28 Nov. 2007. Heart Failure. Heart Failure _Mechanisms Heart Failure CV Diseases-Review Management of Heart failure Medical Surgical Other Systems. C.H.F - Mechanisms.

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HEART FAILURE

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  1. HEART FAILURE Jagdish Butany Univ. Toronto & Toronto General Hospital 28 Nov. 2007

  2. Heart Failure • Heart Failure _Mechanisms Heart Failure • CV Diseases-Review • Management of Heart failure Medical Surgical • Other Systems

  3. C.H.F - Mechanisms • Connective Tissue Increased • Result: “Interstitial Heart Disease” • Altered: Systolic and diastolic function

  4. CHF • Myocardial diseases • Coronary Artery Disease • Valvular disease • Interstitial Diseases

  5. Lungs in C.H.F. (2) • Pulmonary lymphatics drain into Systemic veins. Elevated systemic venous pressure (in C.H.F.). Decreased lymphatic flow. Worsen pulmonary edema.

  6. Mortality in C.H.F. • Prognosis: Poor • Severe Symptoms: 50% 1 year • Less Severe: 50% in 3-4 years

  7. Complications of M .I. • Sudden Death -Arrhythmias • Acute Heart Failure • (Transmural Infarction) • (Subendocardial Infarction) • Mural Thrombosis • Myocardial Rupture : Free wall • I V Septum • Papillary Muscle • Left ventricular Aneurysm /Mural Thrombus • Chronic Congestive Heart Failure • Pericarditis

  8. Heart Failure • Heart Failure _Mechanisms Heart Failure • Diseases-Review • Management of Heart failure Medical Surgical • Other Systems

  9. C.H.F - Mechanisms • ? Defects in membrane transport enzymes Na+ - K+ - ATPase, or Ca2+ • Sarcoplasmic Reticulum: Ca2+ uptake and release, defects • Myocardial beta-adrenergic receptors decreased

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