1 / 9

Platelets

Platelets. Matea Mrčelić, 2 nd year University of Zagreb, School of Medicine 2013/2014 Mentor: A. Žmegač Horvat. Definition. Small colorless anucleate disk - like body of mammalian blood that assists in blood clotting.

mccartneyk
Download Presentation

Platelets

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Platelets Matea Mrčelić, 2nd year University of Zagreb, School of Medicine2013/2014 Mentor: A. Žmegač Horvat

  2. Definition Small colorless anucleate disk-like body of mammalian blood that assists in blood clotting

  3. Process of differentiation helped and accelerated by thrombopoietin Each megakaryocyte produces 5,000 – 10,000 platelets Last step of thrombopoiesis - in bone marrow or in circulation Lifespan: 10 days, old platelets destroyed in spleen

  4. Function

  5. Platelet count • Included in complete blood count • Normal range: 150,000 – 300,000 per microliter • Can be combined with platelet function test • Useful test for patients receiving anticoagulant therapy

  6. Thrombocytopenia • Decrease of plateletcount - below 50,000 per microliter •  Symptoms: easy bruising, frequent bleeding from the gums, nose, or GI tract, thrombocytopenic purpura • Cause: inherited, medications, chemotherapy, alcoholism • Treatment: splenectomy or blood transfusion

  7. Easy bruising Thrombocytopenic purpura

  8. Thrombocytosis • Having more than 450,000 platelets • Primary and secondary – difference in causes • Symptoms: spontaneous blood clots in the arms and legs, which if untreated can lead to heart attack and stroke • Treatment for primary thrombocytosis: plateletpheresis

  9. References • Guyton and Hall Textbook of Medical Physiology, 11th Edition • http://www.platelet-research.org/1/function_hemo.htm# • http://www.hopkinsmedicine.org/heart_vascular_institute/clinical_services/centers_excellence/womens_cardiovascular_health_center/patient_information/health_topics/platelets.html

More Related