This presentation is the property of its rightful owner.
Sponsored Links
1 / 55

动物实验的设计和实施 PowerPoint PPT Presentation


  • 51 Views
  • Uploaded on
  • Presentation posted in: General

动物实验的设计和实施. 动物实验设计概论. For scientific, ethical and economic reasons, it is important to design animal experiments well, to analyze the data correctly, and to use the minimum number of animals necessary to achieve the scientific objectives. 动物实验设计概论. 一般来说,动物实验的研究工作应该明确描述:: 研究的目的和 / 或者需要验证的假说。

Download Presentation

动物实验的设计和实施

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


7024016


7024016

  • For scientific, ethical and economic reasons, it is important to design animal experiments well, to analyze the data correctly, and to use the minimum number of animals necessary to achieve the scientific objectives


7024016

  • /


7024016

  • 1,

  • 2


7024016

  • 1,

  • 2

  • 3


7024016


7024016

3

  • 1

  • 2

  • 3


7024016

3R

NO.1 Reduction

NO.2 Replacement

NO.3 Refinement


7024016

  • 1(

  • 2

  • 3


7024016

  • 1

    2

  • 1

    2

    3


7024016

1

A:

B:

C: -=

D:

A:

B:


7024016

2

A

B:


7024016

2

C:

D:

GLP( good laboratory practice)SOPstandard operating procedure)


7024016

1 2

3 4

3~4

5%~10%

20~40HZ,


7024016

1

  • 2


7024016

3

  • A:

    B:

    C:


7024016

1

A:

B

C

D

2

A

B

C

D


7024016

3


7024016


7024016


7024016

  • A

  • B:


7024016


7024016


7024016


7024016


7024016

  • :

    A12

    B:


7024016

1

  • IACUC


7024016

2


7024016

3

  • IACUC


7024016

4

  • 5


7024016

  • A

  • B

  • C3R


7024016


7024016

  • DNA

  • 5% 501%300


7024016


7024016


7024016


7024016


7024016

  • Pc:

  • Pe:

  • qc=1- Pc

  • qe=1- Pe

  • d = Pc&Pe

  • C

0.05 0.01

0.8 7.85 11.68

0.9 10.51 14.88.


7024016

  • 20%50%80%P=0.050.8,a=0.05) , C=7.85

  • Pc=0.2

  • Pe=0.5

  • qc=1- 0.2

  • qe=1- 0.5

  • d = 0.3

  • C=7.85


7024016

4

  • S:

  • d


7024016

  • 400gSD=23g20g90%5%10.51


7024016


7024016


7024016


7024016


7024016

  • www.biomath.info

  • www.davidonlane.com/hyperstst/power.html

  • www.zoology.ubc.ca/krebs/power.html

  • www.stat.uiowa.edu/rlench/power/index.html

  • www.lal.org.uk/hbook14.htm

  • www.biomath.info

  • www.davidonlane.com/hyperstst/power.html

  • www.zoology.ubc.ca/krebs/power.html

  • www.stat.uiowa.edu/rlench/power/index.html

  • www.lal.org.uk/hbook14.htm


7024016


7024016


7024016

  • 1


7024016

1

  • 2 2


7024016

  • 2


7024016

  • 3


7024016

  • 1

  • 2

  • 3


7024016


  • Login