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FASCIOLOPSIS BUSKI

FASCIOLOPSIS BUSKI. Introduction. Fasciolopsis buski is known scientifically as the largest intestinal fluke in humans.Infection occurs primarily in Asia and the Indian subcontinent, especially in area where humans raise pigs and consume freshwater plants, so this helminth is also

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FASCIOLOPSIS BUSKI

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  1. FASCIOLOPSIS BUSKI

  2. Introduction Fasciolopsis buski is known scientifically as the largest intestinal fluke in humans.Infection occurs primarily in Asia and the Indian subcontinent, especially in area where humans raise pigs and consume freshwater plants, so this helminth is also named as “giant Asian intestinal fluke”.This giant parasite has even been described as “meat worm” or “reddish worm” in traditional Chinese medical book.

  3. I. Morphology (1) Adult • Long elliptic, flesh-colored, looks like • a slice of raw meat • The size: 20-75×8-20×0.5-3mm • The ventral sucker (filler-like • / infundibular ) is larger and near by the • much smaller oral sucker • Two coral-liked(珊瑚) testes are located • in the posterior half of the body No seminal receptacle

  4. ventral sucker is 3-4 times larger than oral sucker oral sucker uterus cecum ovary vitellaria testes

  5. (2) Egg The thinner shell with an operculum (not so obvious) encloses an ovum and 20-40 yolk cells Slightly yellow in color 130-140×80-85µm (the largest helminth egg) Oval / long elliptic in shape

  6. The first intermediate host： Segmentina

  7. water caltrop水红菱 茭白cane shoot Water chestnut荸荠 The second intermediate host： Aquatic plant vector

  8. II. Life cycle • Site of inhabitation: small intestine, • 2. Infective stage: metacercaria, • 3. Infective route and mode: eating raw water • plants with metacercariae, • 4. Intermediate hosts: Planorbis snail, • 5. Reservoir hosts: pig, • 6. Life span: 1-4 years, • 7. Egg output: 15,000/worm/day.

  9. Adolescent Adult Eggs Duodenum In Human Body 3 monthsare discharged man eats metacercariae in feces on raw water plants ──────────────────────────── Metacercaria Eggs get into water encystations on theIn Water25-30℃ surface of water plants2-3 months3-4weeks Miracidiahatch out invades Many cercaria asexual reproduction Planorbis snail Many daughter rediae Many mother rediae Sporocysts

  10. III. Pathology and Symptomatology • The enteritis due to worms’ adhesion manifests abdominal discomfort and • diarrhea. • 2. Malnutrition results from the worms • sharing food with the host and diarrhea.

  11. IV. Diagnosis Stool examination: 1. Direct fecal smear, 2. Water sedimentation method

  12. V. Treatment and Prevention 1. The treatment of the patients, carriers and pigs Drug of choice is praziquantel. Other effective drugs include hexachloroparaxylene, bithionol (bitin). The drug for pig is dipterex (敌百虫). 2. Prevention (1) Health education (2) Deal with night soil. (3) Avoid feeding pigs on raw water plants

  13. VI. Epidemiology This disease is prevalent in Southeast Asia,China, Japan, Korea, Thailand, Burma, Kampuchea, Vietnam, Bangladesh, Philippines,Indonesia, Malaya and India . In China it is found in 18 provinces, city and autonomic region except north and west regions. The prevalence of fasciolopiasis is relative to growing water plants and feeding pigs on water plants.

  14. Thank you !

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