Detecting Infectious HIV in Human Milk. Miles W. Cloyd, Ph.D. Professor Department of Microbiology & Immunology University of Texas Medical Branch Galveston, TX. Does human milk contain infectious HIV?. Question?. What is known?.
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Detecting Infectious HIV in Human Milk
Miles W. Cloyd, Ph.D.
Department of Microbiology & Immunology
University of Texas Medical Branch
-HIV RNA detectable by PCR in milk of 60-90% of HIV + mothers (usually requires testing of multiple samples from each mother).
-Correlation of milk HIV RNA levels with higher plasma HIVloads, lower blood CD4 counts, detection of HIV DNA in maternal genital secretions, and mastitis.
-Milk contains several inhibitors of HIV infectivity (lactoferrin, SLPI, EPO, antibodies)
-Infectious HIV has not been detected.
No Virus Produced
Memory (some with HIV)