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Department of Radiology University of California San Diego

Department of Radiology University of California San Diego. MR Imaging of the Brain. John R. Hesselink, M.D. MR System Components. Transmitter. Gradient Amplifier. RF Coil. Gradient. Computer. Gradient. RF Coil. Magnet. Receiver. Digitizer. Source of Signal and Contrast.

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Department of Radiology University of California San Diego

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  1. Department of Radiology University of California San Diego MR Imaging of the Brain John R. Hesselink, M.D.

  2. MR System Components Transmitter Gradient Amplifier RF Coil Gradient Computer Gradient RF Coil Magnet Receiver Digitizer

  3. Source of Signal and Contrast Proton density T1 relaxation time T2 relaxation time Flow effects MR Imaging

  4. RF TR TE Signal Spin-echo Pulse Sequence Single Echo T1-weighted 1st echo 2nd echo

  5. RF TR TE TE Signal Spin-echo Pulse Sequence Dual Echo T2-weighted 1st echo 2nd echo

  6. T2-Weighted Images

  7. Proton Density Weighted Images

  8. Normal FLAIR Images TR = 6000 msec, TI = 2000 msec, TE = 102 msec

  9. T1-Weighted Images

  10. MR Signal ofBrain Lesions

  11. T1W T2W Solid Brain Lesion PDW

  12. T1W Cystic Lesion FLAIR T2W 236

  13. Subacute Hemorrhage PDW T1W T2W

  14. T2W FLAIR Acute Hemorrhage T1W GRE

  15. History: 9 y/o boy with prior head trauma 466

  16. Hemorrhage Sequence Gradient-echo

  17. Fat or Lipoma T2W PDW T1W

  18. MR Signal Intensities T2WI PD/FLAIR T1WI Solid mass Bright Bright Dark Cyst Bright Dark Dark Subacute blood Bright Bright Bright Acute & chronic blood Dark Dark Gray Fat Dark Bright Bright

  19. Acute Stroke Sequence Diffusion Weighted Imaging

  20. MR Angiography

  21. MR Spectroscopy Dx: Anaplastic astrocytoma > GBM

  22. Sagittal T1-weighted images Axial T2-weighted images Axial FLAIR images Diffusion-weighted images Gradient-echo images Axial T1-weighted images Gadolinium: Axial & Coronal T1 Brain Screening Protocol

  23. History: 46 y.o. man with headaches & increasing confusion 2 1 T2W PDW

  24. 4 3 T1W T1W 5 {Page 2} T1W / Gd

  25. Increasing confusion {Page 3} 6 7 Dx: Meningioma & right MCA infarct

  26. Student Cases "May the FORCE be with you!"

  27. History: 69 y/o man with nausea & memory deficits for several weeks Case 1 413

  28. {Page 2} Dx: Glioblastoma

  29. Case 2 History: 5 y/o girl with seizures 361

  30. {Page 2}

  31. {Page 3} Dx: Amoebic abscesses

  32. Case 3 History: 62 y.o. man with mumbling speech 1 2 26

  33. {Page 2} 3 4

  34. Mumbling speech {Page 3} 5 6

  35. {Page 4} 7 8 Dx: Enhancing subacute infarct

  36. Case 4 History: 48 y.o. male with a sensorineural hearing loss 2 1

  37. 3 5 4 {Page 2} Dx: Acoustic neuroma

  38. Case 5 History: 48 y.o. man with headaches & confusion 1 2 32

  39. {Page 2} 3 4

  40. 5 {Page 3} 7 6

  41. 8 9 {Page 4} 10 Dx: Brain metastases - Lung carcinoma

  42. Case 6 History: 36 y.o. man with seizures 2 1

  43. 5 3 4 History: Seizures {Page 2}

  44. 6 {Page 3} 7 8 Dx: AVM & basilar tip aneurysm

  45. Case 7 History: 62 y/o woman with headaches

  46. {Page 2} Dx: Arachnoid cyst

  47. Case 8 History: 27 y.o. man with increasing confusion & lethargy 1 2 5

  48. Confusion and lethargy {Page 2} 3 4

  49. 5 {Page 3} 6 Dx: Herpes simplex encephalitis

  50. 1 2 3 History: 72 y.o. woman with headaches Case 9 49

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