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The Effects of Resveratrol and Melatonin on Drosophila melanogaster with Paraquat Induced Oxidative Stress. By Anthony Anastasio. Need. Figure 1 Over the passed 6 years, disorders from alcohol have increased. Figure 2 Wine still remains the leased consumed alcoholic beverage .

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slide1

The Effects of Resveratrol and Melatonin on Drosophila melanogaster with Paraquat Induced Oxidative Stress

By Anthony Anastasio

slide2
Need

Figure 1

Over the passed 6 years, disorders from alcohol have increased

Figure 2

Wine still remains the leased consumed alcoholic beverage

resveratrol
Resveratrol
  • Found in the skin of grapes that are used in the fermentation of red wine.
  • Found in plants as a defense system against disease.
bass 2007
Bass (2007)
  • When drosophila exposed to resveratrol, no increase in lifespan is shown

Effect of Resveratrol on the Life span of C. Elegans

bauer 2004
Bauer (2004)
  • Drosophila showed an increase in lifespan with resveratrol supplements
bonilla and molero 2006
Bonilla and Molero (2006)
  • Drosophila exposed to Melatonin, Serotonin, Lipoic acid, and Ascorbic acid

The survivability of Drosophila shown after paraquat induced oxidative stress with different pre exposures

purpose
Purpose
  • To determine the effects of resveratrol and melatonin on the survival rate of drosophila after paraquat induced oxidative stress.
hypothesis
Hypothesis
  • Null Hypothesis- Drosophila will have the same survival rate after paraquat induced oxidative stress in all groups and no change in life span will occur.
  • Alternative Hypothesis- Drosophila that are pre-exposed to resveratrol and melatonin will have a higher survival rate after paraquat induced oxidative stress and a longer life span then the control group.
do ability
Do-ability
  • Drosophila cultures are available
  • Exposure to Resveratrol and Melatonin
  • Procedures that been done in lab
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