The Effects of Resveratrol and Melatonin on
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The Effects of Resveratrol and Melatonin on Drosophila melanogaster with Paraquat Induced Oxidative Stress. By Anthony Anastasio. Need. Figure 1 Over the passed 6 years, disorders from alcohol have increased. Figure 2 Wine still remains the leased consumed alcoholic beverage .

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By anthony anastasio

The Effects of Resveratrol and Melatonin on Drosophila melanogaster with Paraquat Induced Oxidative Stress

By Anthony Anastasio


By anthony anastasio

Need

Figure 1

Over the passed 6 years, disorders from alcohol have increased

Figure 2

Wine still remains the leased consumed alcoholic beverage


Oxidative stress

Oxidative stress


Antioxidants

Antioxidants


Resveratrol

Resveratrol

  • Found in the skin of grapes that are used in the fermentation of red wine.

  • Found in plants as a defense system against disease.


Bass 2007

Bass (2007)

  • When drosophila exposed to resveratrol, no increase in lifespan is shown

Effect of Resveratrol on the Life span of C. Elegans


Bauer 2004

Bauer (2004)

  • Drosophila showed an increase in lifespan with resveratrol supplements


Bonilla and molero 2006

Bonilla and Molero (2006)

  • Drosophila exposed to Melatonin, Serotonin, Lipoic acid, and Ascorbic acid

The survivability of Drosophila shown after paraquat induced oxidative stress with different pre exposures


Purpose

Purpose

  • To determine the effects of resveratrol and melatonin on the survival rate of drosophila after paraquat induced oxidative stress.


Hypothesis

Hypothesis

  • Null Hypothesis- Drosophila will have the same survival rate after paraquat induced oxidative stress in all groups and no change in life span will occur.

  • Alternative Hypothesis- Drosophila that are pre-exposed to resveratrol and melatonin will have a higher survival rate after paraquat induced oxidative stress and a longer life span then the control group.


Budget

Budget


Do ability

Do-ability

  • Drosophila cultures are available

  • Exposure to Resveratrol and Melatonin

  • Procedures that been done in lab


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