Chapter 9 Cell Communication Dr. Joseph Silver. this chapter deals with how cells receive messages what changes take place in the cell and what changes take place in the nucleus. how one cell signals another is defined by the distance from the source to the receptor 5 types are described.
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some receptors such as steroid hormone receptorsare not in the membranebecause the message can pass right throughthe membraneso activation takes place inthe cytoplasm
there are three very importantkinases in cellsRTK, RSK, RTyKthese kinases add or remove phosphatefrom molecules and influence most reactions taking place in every cell
look at fig 9.8 to seeamplification of eventsanother word for multiplicationin some cases instead of a 1 to 1 relationshipthere isa 1 to 2, then 2 to 4, then 4 to 8 relationshipas more and more reactions or systems are amplified or inhibited
We have previously studiedhomeodomainsand multienzyme complexesnow they are giving in fig 9.9another name for a multienezyme complexa scaffold proteinwhich holds in placea number of kinase cascadesfor increased efficiency