Chapter 9 cell communication dr joseph silver
Sponsored Links
This presentation is the property of its rightful owner.
1 / 26

Chapter 9 Cell Communication Dr. Joseph Silver PowerPoint PPT Presentation


  • 52 Views
  • Uploaded on
  • Presentation posted in: General

Chapter 9 Cell Communication Dr. Joseph Silver. this chapter deals with how cells receive messages what changes take place in the cell and what changes take place in the nucleus. how one cell signals another is defined by the distance from the source to the receptor 5 types are described.

Download Presentation

Chapter 9 Cell Communication Dr. Joseph Silver

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


Chapter 9Cell CommunicationDr. Joseph Silver


this chapter deals withhow cells receive messageswhat changes take place in the celland what changes take place in the nucleus


how one cell signals another is defined by the distance from the source to the receptor5 types are described


-direct contact-paracrine-endocrine-synaptic-autocrine


the key to everything thatgoes on in a cell is phosphorylationordephosphorylation


start or stopinhibit or activateturn on or turn offall happen byadding or removing a phosphate functional group


receptors are definedby their location- on a membrane- in a membrane- trans membrane- cytoplasmic


there are three types ofmembrane receptors- channel receptors-enzyme receptors-G protein-coupled receptors


some receptors such as steroid hormone receptorsare not in the membranebecause the message can pass right throughthe membraneso activation takes place inthe cytoplasm


there are three very importantkinases in cellsRTK, RSK, RTyKthese kinases add or remove phosphatefrom molecules and influence most reactions taking place in every cell


see fig 9.6 to see- message to receptor linkage- autophosphorylation- activation of protein by phosphorylationthen


Go to fig 9.7 to see- activation of 2nd and 3rd messengers- activation of enzyme- result of work stimulated by enzyme activity


look at fig 9.8 to seeamplification of eventsanother word for multiplicationin some cases instead of a 1 to 1 relationshipthere isa 1 to 2, then 2 to 4, then 4 to 8 relationshipas more and more reactions or systems are amplified or inhibited


We have previously studiedhomeodomainsand multienzyme complexesnow they are giving in fig 9.9another name for a multienezyme complexa scaffold proteinwhich holds in placea number of kinase cascadesfor increased efficiency


Now look at fig 9.11 & 9.12to see the whole processfrom ligand binding to receptortoresponse by cell


At the end of the chapter they want you to understand thatthere are many kinds of 2nd and 3rd etc. messengers


Cyclic AMPinositol phosphatescalcium


  • Login