SPUC
Download
1 / 34

SPUC December 15, 2008 [email protected] - PowerPoint PPT Presentation


  • 112 Views
  • Uploaded on

SPUC December 15, 2008 [email protected] CASE 1. CASE 1 Diagnosis: Coccidioidomycosis. Coccidioidomycosis. Diagnosis Coccidioidomycosis - Endemic fungal infection of the desert southwestern United States - Generally a self-limited illness in healthy persons.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about ' SPUC December 15, 2008 [email protected]' - malise


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript

SPUC

December 15, 2008

[email protected]





Diagnosis Coccidioidomycosis

- Endemic fungal infection of the desert

southwestern United States

- Generally a self-limited illness in healthy persons.

- Immunosuppressed persons who contract it

are at increased risk for disseminated infection

Janis E. Blair, MD; Jerry D. Smilack, MD; Sean M. Caples, DO. Coccidioidomycosis in Patients With Hematologic Malignancies

Arch Intern Med. 2005;165:113-117






  • Mesenchymal tumors of the gastrointestinal tract are less frequent than epithelial neoplasms but they are by no means rare.

  • Gastrointestinal stromal tumors (GISTs):

  • Most common mesenchymal tumor of the GI tract

  • Histopathology:

    • cellular spindled

    • epithelioid

    • pleomorphic lesions

    • express KIT (CD117) and CD34 proteins


  • True leiomyomas of the muscularis propria: frequent than epithelial neoplasms but they are by no means rare.

  • Common in the esophagus and rare in the gastric body and antrum

  • Most frequent mesenchymal tumor of the esophagus:

    • Leiomyomas outnumber GIST by a ratio of 3 to 1


CASE 3 frequent than epithelial neoplasms but they are by no means rare.


Case 3 Diagnosis: Thymoma AB frequent than epithelial neoplasms but they are by no means rare.


Thymoma Type B1 frequent than epithelial neoplasms but they are by no means rare.


CLASSIFICATION OF THYMOMAS frequent than epithelial neoplasms but they are by no means rare.


CASE 4 frequent than epithelial neoplasms but they are by no means rare.


Case 4 Diagnosis: Giant Cell Tumor of Tendon Sheet frequent than epithelial neoplasms but they are by no means rare.


CASE 5 frequent than epithelial neoplasms but they are by no means rare.


Case 5 Diagnosis: Fibrous Dysplasia frequent than epithelial neoplasms but they are by no means rare.


Fibrous dysplasia, benignt tumor (developmental arrest) frequent than epithelial neoplasms but they are by no means rare.

Components of normal bone are present, but they fail to

differentiate into mature structures.

Occurs as one of three clinical patterns:

1. involvement of a single bone (monostotic)

2. involvement of multiple bones( polyostotic)

3. Polyostotic disease, associated with cafe au lait skin pigmentations and endocrine abnormalities, precocious puberty (McCune- Albright syndrome). Somatic, not hereditary. Skeletal, skin, and endocrine lesions from G protein that constitutively activates adenyl cyclase with resultant cyclic adenosin monophosphate overproduction and cellular hyperfunctioning.


CASE 6 frequent than epithelial neoplasms but they are by no means rare.


Case 5 Diagnosis: Chemical / Reactive Gastropathy frequent than epithelial neoplasms but they are by no means rare.


  • CHRONIC, REACTIVE (CHEMICAL) GASTROPATHY frequent than epithelial neoplasms but they are by no means rare.

  • - Very common in current clinical practice.

  • Changes usually more prominent in the prepyloric region

  • The usual underlying causes include chronic bile reflux and long-term NSAID intake.


CHRONIC, REACTIVE (CHEMICAL) GASTROPATHY frequent than epithelial neoplasms but they are by no means rare.

  • The histopathologic features:

  • mucosal edema

  • congestion

  • fibromuscular hyperplasia in the lamina propria

  • foveolar hyperplasia with a corkscrew appearance in the most severe forms

  • The foveolar epithelium characteristically: reactive nuclear features and reduction of mucin.

  • The epithelial changes occur with little background chronic inflammation.

Arch Pathol Lab Med—Vol 132, October 2008


ad