SPUC December 15, 2008 [email protected] CASE 1. CASE 1 Diagnosis: Coccidioidomycosis. Coccidioidomycosis. Diagnosis Coccidioidomycosis - Endemic fungal infection of the desert southwestern United States - Generally a self-limited illness in healthy persons.
- Endemic fungal infection of the desert
southwestern United States
- Generally a self-limited illness in healthy persons.
- Immunosuppressed persons who contract it
are at increased risk for disseminated infection
Janis E. Blair, MD; Jerry D. Smilack, MD; Sean M. Caples, DO. Coccidioidomycosis in Patients With Hematologic Malignancies
Arch Intern Med. 2005;165:113-117
Mesenchymal tumors of the gastrointestinal tract are less frequent than epithelial neoplasms but they are by no means rare.
Components of normal bone are present, but they fail to
differentiate into mature structures.
Occurs as one of three clinical patterns:
1. involvement of a single bone (monostotic)
2. involvement of multiple bones( polyostotic)
3. Polyostotic disease, associated with cafe au lait skin pigmentations and endocrine abnormalities, precocious puberty (McCune- Albright syndrome). Somatic, not hereditary. Skeletal, skin, and endocrine lesions from G protein that constitutively activates adenyl cyclase with resultant cyclic adenosin monophosphate overproduction and cellular hyperfunctioning.
Arch Pathol Lab Med—Vol 132, October 2008