Responsive Drug Delivery System. Presenter: Bo He 12/10/03. Outline. Traditional drug dosing & introduction to responsive drug delivery systems Commercially available sensors & drug delivery systems Responsive drug delivery systems under development Challenge & perspective.
Responsive Drug Delivery System
A semi-interpenetrating polyacrylamide (PAAm) hydrogel
Antigen—rabbit immunoglobulin G( rabbit IgG)
Antibody—goat anti-rabbit IgG (GAR IgG)
Takashi Miyata et al., Nature, vol 399 ,766
Effect of free antigen concentration on the hydrogen swelling ration
Antigen recognition by antigen-antibody semi-IPN hydrogel