Ncrn quinquennial review
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NCRN Quinquennial review. David Cameron. QQ Review. Who & By whom What Where When WHY? Where next…. QQ review – who?. Review of the Co-ordinating centre NOT OF THE NETWORKS Review party UKCRN lead DH CRUK NCRI Independents – External. QQ review – what?.

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NCRN Quinquennial review

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Ncrn quinquennial review

NCRN Quinquennial review

David Cameron


Qq review

QQ Review

  • Who & By whom

  • What

  • Where

  • When

  • WHY?

  • Where next….


Qq review who

QQ review – who?

  • Review of the Co-ordinating centre

    • NOT OF THE NETWORKS

  • Review party

    • UKCRN lead

      • DH

      • CRUK

      • NCRI

      • Independents – External


Qq review what

QQ review – what?

  • Submission of paperwork 15 Nov

  • Face-to-face on 21st January 2009

  • Review of past performance

  • Review of processes/ principle

  • Discussion about future vision…


Qq review why

QQ review – why?

  • Review of annual grant to fund CC

    • Are we (not you) value for money?

  • Review contribution of CC to Cancer research

  • Review of all TCRNs a few years in…


Qq review where next

QQ review – where next?

  • Report achievements to date

  • Define NCRN’s place in new universe

  • Redefine key relationships

  • Address challenges

  • Propose developments to continue to meet original aim

    “Improving the outcome for cancer patients

    by recruiting more patients to trials”


Summary of past

Summary of past

  • Continued increase in accrual

    • Cancer RCTs dipped….starting to rise

    • Overall Cancer accrual up

    • Overall RCT accrual up

  • Evidence that not as many sites open in 2007/08 as in 2003/04

    • EUCTD & other R&D/ research governance

  • Evidence of increasing follow-up burden

Accrual ↑ whilst available trials and resource ….well done!!


Initiatives

Initiatives

  • Follow-up burden

    • NCIN/NYCRIS post

    • Project officers – breast/lymphoma/urology

  • Funding

    • Re-distribution of underspend/ NRF

      • Pump-priming initiatives

  • Novel agents

  • Screening/ prevention studies

  • Data quality exercise


Forward look

Forward look

  • Screening/diagnosis/prevention trials

    • No central co-ordination

      • Individual trials may…

        • link to CSG

        • Ask for NCRN resource (& complain if they don’t get some..)

        • Recruit from very different parts of NHS

      • Portfolio of trials

        • Not necessarily strategically aligned

    • Now an NCRI and CRS priority……

    • Clearly in the NCRN portfolio

      • Yet we are not solely responsible for accrual…


Breakout sessions

Breakout sessions

  • 5 Clusters

  • CC staff and visitors (CRUK, NCRI)

  • Devolved nations

    • Can join a cluster

    • Can form their own cluster

    • Can hit the shops or gym………..

  • Reactions to the following suggestions

  • Any other comments on current accrual


Key questions for rnms 1

Key questions for RNMs - 1

  • Flexible funding

    • CC retains underspend and/or some of FSF

  • Redistribution exercise

    • Bidding system – all English networks

    • Targetted resources

    • Priority

      • NCRI or NIHR or loca

    • Fixed term – CLRN or commercial uptake

      • Hopefully 1-2 years’ funding

How can you make this work in your network/ NHS host?


Key questions for rnms 2

Key questions for RNMs - 2

  • Screening and Prevention

  • NOW IN THE CANCER PORTFOLIO

  • NCRN cannot supply all the resource

  • National and local engagement with

    • CLRN

    • PCRN

    • Research Funders

  • CC will have nominated lead for this area

How will you do this locally?


Key questions for rnms 3

Key questions for RNMs - 3

  • Geographical alignment

  • Cancer networks

    • Patient journeys

    • Clinical links

    • NSSGs and MDTs

  • Comprehensive networks

    • Source of service support cost

    • NCRN income generating for CLRNs

How to have two partners?


Key questions for rnms 4

Key questions for RNMs - 4

  • Initiatives

  • NCRI

    • Supac, lung cancer, prostate cancer

    • Screening/ prevention trials

  • NIHR

    • Commercial trials

    • More RCTs

    • Complete studies on time

How can you make your network respond to initiatives?


Key questions for rnms 5

Key questions for RNMs - 5

  • Networking

    • Inter-hospital referrals for studies

    • Inter-network referrals for studies

  • Overcoming perceived NHS barriers

  • Encourage knowledge of full portfolio

    • Commercial trials and non-commercial

    • Across the network

    • In adjacent networks

What can you do to enhance accrual by better networking?


Key questions for rnms 6

Key questions for RNMs - 6

  • Data quality

    • Accruing patients is not enough

      • Accurate data needed

    • No clear definition

      • Timeliness, accuracy, completeness

  • Sponsor/ site responsibility

    • BUT……NCRN needs to know that our data is good!

  • Round-robin approach

    • Site visits with CTU staff + NCRN staff from another network

What problems and benefits can you see from this?


Questions not for qq

Questions not for QQ

  • End sept meeting with NHS chief execs……

  • How do we encourage the NHS to support research

    • Consultants

    • Nurses

      • CNS, out-patient and in-patient staff

    • Service departments

      • Path/radiology/pharmacy

      • HR / Finance etc.


Vision

Vision

  • NCRN CC here to support the networks & funders

  • Continue the good work you have already done

  • Remain at the forefront of world cancer trial accrual

  • Drive the engagement with the new NHS research world…..be patient!

  • Embed research in the NHS

  • Work collectively not individually

    • NCRI

    • CRUK & other funders

    • CLRN

    • PCRN & other TCRNs


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