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30.08.2014. Master title. International Molecular Exchange Consortium - IMEx Sandra Orchard EMBL-EBI. 5. EBI is an Outstation of the European Molecular Biology Laboratory. IMEx. PSICQUIC gives access to multiple databases and large amounts of data

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Master title

30.08.2014

Master title

  • International Molecular Exchange Consortium - IMEx

  • Sandra Orchard

  • EMBL-EBI

5

EBI is an Outstation of the European Molecular Biology Laboratory.


Master title

IMEx

PSICQUIC gives access to multiple databases and large amounts of data

BUT IntAct, DIP, MINT provide original curation, many databases (IRefIndex, APID, I2D, String..) do not curate but merge data from curation resources. IntAct data is repeated in multiple other resources

Curation databases formed a consortium to provide users with a single, non-redundant dataset


Master title

IMEx

Independent molecular interaction resources all separately funded and with their own curation priorities

Spent several years developing Common curation standards for detailed curation and a joint curation manual

Common data formats – all data downloadable in PSI formats (PSI-MI MITAB/XML)

IMEx is an instance of PSICQUIC, specific records are tagged as part of the IMEx set and only these records are searchable and downloadable on the website.


Master title

IMEx

  • Coordinated & non-redundant curation – databases ensure that each paper is curated once, and once only by a single member database.

  • Each paper is registered with a central database, IMEx Central, which ensures curation is not repeated by a second database


Master title

IMEx

Common accession number space – all submitted data gets an IMEx ID and is searchable on the IMEx site, the site of submission and multiple member database sites


Imex partners

IMEx partners

IntAct – Active

DIP – Active

MINT – Active

MatrixDB – Active

MPIDB - Active

I2D - Active

Innate DB – Active

Molecular Connections – Active

(MPACT – Inactive)

(BIND – Inactive)

BioGRID - Observer


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www.imexconsortium.org

7


Imex statistics

IMEx statistics

Sept 2011 - 172,906 binary interactions from 4,387 publications


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IMEx

In production mode since February 2010

Since 3/2009 supported by the European Commission under PSIMEx, contract number FP7-HEALTH-2007-223411, with additional partners Vital-IT, Nature, Wiley, BiaCore (GE), U. Maryland, CSIC, TU Munich, MIPS, SCBIT (Shanghai)


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