1 / 24

Intrathoracic Complications of HIV

Intrathoracic Complications of HIV. Jay Mizzell 2.2.06. Roadmap. Infectious manifestations PCP TB Bacterial pneumonia Noninfectious manifestations Kaposi sarcoma Others . Incidence of AIDS defining OI in men v women 1996-1998. Pneumocystis carinii pneumonia.

madge
Download Presentation

Intrathoracic Complications of HIV

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Intrathoracic Complications of HIV Jay Mizzell 2.2.06

  2. Roadmap • Infectious manifestations • PCP • TB • Bacterial pneumonia • Noninfectious manifestations • Kaposi sarcoma • Others

  3. Incidence of AIDS defining OI in men v women 1996-1998

  4. Pneumocystis carinii pneumonia • Most common opportunistic infection in US • CD4 counts <200 • Fever, dyspnea, nonproductive cough

  5. PCP Radiographic Features • Classic findings • Interstitial or alveolar infiltrates • Diffuse • Bilateral • Atypical or normal findings are common

  6. Typical PCP

  7. Typical PCP

  8. Typical PCP

  9. Tuberculosis • 4% of all US AIDS cases • More common worldwide • Most common manifestation of HIV • Most common cause of death with AIDS

  10. TB Radiographic Features • Infection early in HIV course (CD4 > 400) • 1° TB • Post 1° TB • Infection late in HIV course (CD4 < 200) • Nodular interstitial pattern • Diffuse, bilateral, coarse • Hilar adenopathy • No cavitation

  11. 1° TB

  12. 1° TB

  13. Ranke Complex

  14. Post 1° TB

  15. Post 1° TB

  16. Atypical TB

  17. Atypical TB

  18. Bacterial Pneumonia • More common than PCP in US • Predilection for IVDU • Encapsulated bacteria • Esp S. pneumoniae and H. influenzae • Radiographically indistinguishable

  19. Kaposi Sarcoma • Caused by HHV8 • Almost exclusively in MSM • Appears at lower CD4 counts • Mucocutaneous concurrent with pulmonary manifestations

  20. KS Radiographic Features • Bilateral middle-lower lung opacities • Nodular, ill-defined • Perihilar distribution • Intrathoracic adenopathy • Bronchial wall thickening • Pleural fluid

  21. Kaposi Sarcoma

  22. Kaposi Sarcoma

  23. Other Noninfectious Findings • Non-Hodgkin lymphoma • Lymphocytic Interstitial Pneumonitis • Nonspecific Interstitial Pneumonitis

More Related