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The Gonzalez Therapy. By Laura Wiseley. Prevalence of Pancreatic Cancer. Fifth leading cause of cancer death 27,000 annual deaths in the U.S. Overall survival rate 25% at 1 year 10% at 2 years ~4% at 5 years 25% of cases eligible for surgery Post-op survival <20% at 5 years.

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The gonzalez therapy l.jpg

The Gonzalez Therapy

By Laura Wiseley


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Prevalence of Pancreatic Cancer

  • Fifth leading cause of cancer death

    • 27,000 annual deaths in the U.S.

  • Overall survival rate

    • 25% at 1 year

    • 10% at 2 years

    • ~4% at 5 years

  • 25% of cases eligible for surgery

    • Post-op survival <20% at 5 years


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Gonzalez Treatment

  • Enzymes

    • Porcine Pancreatic Enzymes

  • Diet

    • Organic diet, vitamin, mineral, and trace element supplements, Papaya Plus, extracts of animal origins, magnesium citrate

  • Detox

    • Skin cleansing

    • Coffee Enemas


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Pancreatic Enzymes

  • From Special Pigs in New Zealand

  • Clients take up 45 grams

  • Pancreatic enzymes

    • Help eliminate toxic waste from body

    • Help normal cells repair damaged ones

  • Rationale

    • Cancer caused by primordial germ cells

    • Cancer controlled by pancreatic enzymes


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Nutrition Program

  • Organic, not refined, not heavily processed

  • Nine different diets with 10 variations

  • Individualized by “Autonomic Balance” and “Metabolic Type”

    • Sympathetic, Parasympathetic, and Balanced

    • Genetic Type

  • Vegetarian, Metabolizer, Meat

  • Supplements of animal organs, vitamins, minerals, trace elements, papaya, Mg+ citrate


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Skin Cleansing

  • Further detoxifies body

    • May be brushing, soaking, or other cleansing

    • Brushing

      • On dry skin

      • Stimulates and cleanses the lymphatic system

    • Soaking

      • Help to pull toxins out of the skin

      • May be done in vinegar or salt and baking soda

    • Castor oil cleanse


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Coffee Enema

  • Used for ability to stimulate contractions in the gall bladder

    • Causes emptying of toxins into the bowel

  • Historically used in many ancient civilizations

  • Included in the Merck Manual until 1977

  • Decaf enemas

    • Used to prepare for surgery

    • Some use as a laxative


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Coffee Enema

  • How are they done?

    • 3-4 cups of organic brewed coffee

    • Cooled to body temperature

    • Pour into an enema bag

    • Lay down (recommended)

    • Hang bag ~18 inches above body

    • Open valve till coffee reaches surface


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Coffee Enema

  • Insert applicator into rectum

  • Open valve to release coffee into colon

  • Remove enema bag

  • Retain enema for 10-20 minutes

  • Rotate frequently


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Scientific Evidence

  • Mouse Trials

    Objective-To examine the effects of PPE on human xenografts in nude mice

    Methods- 30 male mice injected with PC tumor cells. 15 Given PPE, 15 nothing.

    Results-Mice given PPE lived longer (p<.002) Tumors from PPE mice were smaller

    Negative effects of tumors in control mice earlier and more severe than exp. group


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Evaluation of Pancreatic Proteolytic Enzyme Treatment of Adenocarcinoma of the Pancreas, with Nutrition and Detoxification SupportGonzalez NJ, Isaacs LL. Nutrition and Cancer 33 (2): 117-124, 1999

  • Prospective nonconsecutive case series

  • 11 patients with Stage II or Stage IV PC

  • No chemo- or radiation therapy, nor surgical resection

  • Survival time was the endpoint of study

  • Mean survival time 25.2 months


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Evaluation of Pancreatic Proteolytic Enzyme Treatment of Adenocarcinoma of the Pancreas, with Nutrition and Detoxification SupportGonzalez NJ, Isaacs LL. Nutrition and Cancer 33 (2): 117-124, 1999.

  • 82% survival at 1 year

  • 45% survival at 2 years

  • 36% survival at 3 years

  • 1 patient survived 4 years

    How does this compare to chemotherapy?


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Gemcitabine Compared with Pancreatic Enzyme Therapy Plus Specialized Diet (Gonzalez Regimen) in Treating Patients Who Have Stage II, Stage III, or Stage IV Pancreatic CancerNicholas Gonzalez Clinical Trial

  • NIH Phase III Clinical Trial

    • Definition of Phases I, II, III, and IV

  • Unblinded Intervention Trial

  • Patients choose either the Nutritional Arm or the Chemotherapy Arm

  • Chemotherapy Arm includes tx with Gemcitabine.

  • QOL assessed at 0, 2, 6, and 12 months

  • Patients “assessed” at 1, 3, 5, 7, and 12 months

  • QOL and assessment done every year after first 12 months.


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Gemcitabine Compared with Pancreatic Enzyme Therapy Plus Specialized Diet (Gonzalez Regimen) in Treating Patients Who Have Stage II, Stage III, or Stage IV Pancreatic CancerNicholas Gonzalez Clinical Trial

  • Nutrition Arm (21-day cycle)

    • Pancreatic Enzymes, Papaya Plus and Magnesium Citrate

    • Nutrition Supplementation

    • Moderate vegetarian metabolizer diet

    • Coffee enema 2x/d

    • Daily skin brushing, skin cleansing with castor oil weekly, salt and soda bath weekly

    • Complete liver flush and a “clean sweep and purge” each month


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Conclusions Specialized Diet (Gonzalez Regimen) in Treating Patients Who Have Stage II, Stage III, or Stage IV Pancreatic Cancer

  • Present research shows interesting findings

    • Too small, no control

    • 25 eligible patients were not included

      • Comorbidities, previous tx, “predicted noncompliance”

  • NIH study should give more insight

  • Diet?

  • Coffee enemas have not been shown to improve liver function


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Recommendations Specialized Diet (Gonzalez Regimen) in Treating Patients Who Have Stage II, Stage III, or Stage IV Pancreatic Cancer

  • Keep your eyes peeled for the NIH study in the next few years


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References Specialized Diet (Gonzalez Regimen) in Treating Patients Who Have Stage II, Stage III, or Stage IV Pancreatic Cancer

  • Surac, M. Standop, S. et. al; Pancreatic Enzyme Extract Improves Survival in Murine Pancreatic Cancer. Pancreas. Vol 28(4), pp. 401-412. May 2004.

  • Gonzalez NJ, Isaacs LL. Evaluation of Pancreatic Proteolytic Enzyme Treatment of Adenocarcinoma of the Pancreas, with Nutrition and Detoxification Support. Nutrition and Cancer 33 (2): 117-124, 1999

  • http://nccam.nih.gov/news/19972000/121599.htm

  • clinicaltrials.gov/show/NCT00003851

  • www.meb.uni-bonn.de/cancer.gov/CDR0000410719.htm

  • www.nlm.nih.gov/medlineplus/pancreaticcancer.html

  • www.dr-gonzalez.com

  • http://www.ineedcoffee.com/01/01/enema/

  • http://www.lef.org/magazine/mag2001/aug2001_report_gongalez_01.html


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