DNA Mutations. Biology – 9 th Grade Chapter 10. How does it happen???. Environmental Influences such as: Chemicals or UV Rays Inherited: mutations can be passed down from parent to offspring During copying of DNA , mistakes can occur. Types of Mutations.
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Biology – 9th Grade
ATG TCG CTT TGA CGA MUTATED DNA
Point Mutation Results
Missense Mutation: A different amino acid is produced
Example: GAA codes for Glu-, when the A is changed to a C, the amino acid produced is Asp-.
Nonsense Mutation: The base pair change results in a STOP codon being produced. This may form a nonfunctional protein.
Glu- changes to Val-
What type of mutation is this? Silent, missense or nonsense?
Deletion of Base Pairs
Duplication of Base Pairs
Does not affect the reading frame, with the chance of not affecting the protein being made
Can still be fatal to the carrier, but not always
Types of chromosomal mutations:
-Down’s Syndrome / Trisomy 21
-Turner’s Syndrome / X0 – The entire X chromosome on the 23rd pair is missing
-Edwards Syndrome / Trisomy 18