Parkinson’s: More Than a Movement Disorder. Kelly Condefer, MD Neurologist, Movement Disorders Specialist Wenatchee Valley Medical Center. Fatigue Sleep Problems Autonomic Nervous System Problems Blood pressure regulation Constipation Bladder control Cognitive impairment. Fatigue.
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Parkinson’s: More Than a Movement Disorder
Kelly Condefer, MD
Neurologist, Movement Disorders Specialist
Wenatchee Valley Medical Center
Sleepy. . .
“Walking through molasses”. . .
Decreased activity tolerance. . .
Work with your doctor to determine what might be contributing:
Medication side effect?
A non-Parkinson’s related issue?
Sleep problems in Parkinsons
Adapted from Sleep hygeine recommendations, National Sleep foundation, Michael Thorpy, MD
Autonomic nervous system problems in Parkinson’s
The autonomic nervous system
Bladder function in Parkinson’s
Basal ganglia normally send
signals to the bladder that
keep it from contracting
too soon. . .
Nerve impulses to the bladder
Input from higher centers in brain precisely coordinates the proper contractions and relaxations of muscles to result in normal urinating:
The colon has a large network of interconnected nerves that control its function (the enteric nervous system).
Lewy Bodies have been identified in these cells in the colons of people with Parkinson’s.
Dementia in Parkinson’s
Location of Lewy Bodies in the
brain determines symptoms. . .
Missing pieces in the Parkinson's disease puzzle. Obeso, JA et al. Nature Medicine Volume:16,Pages:653–661; Year published:(2010)