slide1
Download
Skip this Video
Download Presentation
Materials and methods

Loading in 2 Seconds...

play fullscreen
1 / 32

Materials and methods - PowerPoint PPT Presentation


  • 99 Views
  • Uploaded on

Materials and methods. Design Open-label, randomized trial, February 2010 to May 2011, avoiding the summer period Participants recruited from a primary care centre in Sweden , serving a population with a high proportion of non-European residents Inclusion criteria

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about ' Materials and methods' - lucky


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
materials and methods
Materials and methods
  • Design
    • Open-label, randomized trial, February 2010 to May 2011, avoiding the summer period
  • Participants
    • recruited from a primary care centre in Sweden, serving a population with a high proportion of non-European residents
  • Inclusion criteria
    • age 15 years or above and vitamin D deficiency 25(OH)D3 less than 25 nmol /L
  • Exclusion criteria
    • light-sensitive skin
    • ongoing treatment with vitamin D supplementation
    • sunny holidays
    • intake of photosensitive medicine during the study period.
slide4
UVB
  • The average starting dose was 0.36 J
  • increments were about 15% every second treatment session
  • the average maximal (final) dose was 1.20 J.
  • The mean cumulative dose was 9.0 J /cm2
results
Results
  • Significantly greater increase in 25(OH)D3 levels in the NB-UVB treated group compared with the tablet-treated group after 6 weeks of treatment (P = 0.02)
  • in the NB-UVB treated group The 25(OH)D3 levels (mean ± SD) increased from 19.2 ± 6 nmol/L to 75 ± 16.8 nmol/L vs. 23.3 ±4.4 nmol/L to 60.6 ± 16.7 nmol /L in the oral vitamin D3 treated group
results1
Results
  • No significant difference regarding PTH, calcium, albumin or HbA1c levels.
  • Asignificant decrease in PTH
  • A significant increase in calcium levels
limitations
Limitations
  • lack of compliance among the group who took vitamin D3 supplements
  • high dropout number
  • primarily non-European immigrants
conclusion
Conclusion
  • exposure to a small dose of full body NB-UVB radiation three times a week is more efficient in raising vitamin D levels than prescription of a daily oral intake of 1600 IU vitamin D3
slide27

-Vitamin D deficiency is defined as a 25(OH)D below 20 ng/ml (50 nmol/liter)- Vitamin D insufficiency is defined as a 25(OH)D of 21–29 ng/ml

ad