Materials and methods
This presentation is the property of its rightful owner.
Sponsored Links
1 / 32

Materials and methods PowerPoint PPT Presentation


  • 77 Views
  • Uploaded on
  • Presentation posted in: General

Materials and methods. Design Open-label, randomized trial, February 2010 to May 2011, avoiding the summer period Participants recruited from a primary care centre in Sweden , serving a population with a high proportion of non-European residents Inclusion criteria

Download Presentation

Materials and methods

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


Materials and methods

Materials and methods

  • Design

    • Open-label, randomized trial, February 2010 to May 2011, avoiding the summer period

  • Participants

    • recruited from a primary care centre in Sweden, serving a population with a high proportion of non-European residents

  • Inclusion criteria

    • age 15 years or above and vitamin D deficiency 25(OH)D3 less than 25 nmol /L

  • Exclusion criteria

    • light-sensitive skin

    • ongoing treatment with vitamin D supplementation

    • sunny holidays

    • intake of photosensitive medicine during the study period.


Materials and methods

UVB

  • The average starting dose was 0.36 J

  • increments were about 15% every second treatment session

  • the average maximal (final) dose was 1.20 J.

  • The mean cumulative dose was 9.0 J /cm2


Results

Results

  • Significantly greater increase in 25(OH)D3 levels in the NB-UVB treated group compared with the tablet-treated group after 6 weeks of treatment (P = 0.02)

  • in the NB-UVB treated group The 25(OH)D3 levels (mean ± SD) increased from 19.2 ± 6 nmol/L to 75 ± 16.8 nmol/L vs. 23.3 ±4.4 nmol/L to 60.6 ± 16.7 nmol /L in the oral vitamin D3 treated group


Results1

Results

  • No significant difference regarding PTH, calcium, albumin or HbA1c levels.

  • Asignificant decrease in PTH

  • A significant increase in calcium levels


Limitations

Limitations

  • lack of compliance among the group who took vitamin D3 supplements

  • high dropout number

  • primarily non-European immigrants


Conclusion

Conclusion

  • exposure to a small dose of full body NB-UVB radiation three times a week is more efficient in raising vitamin D levels than prescription of a daily oral intake of 1600 IU vitamin D3


R ace skin type

Race ?Skin type ?


Suscreen

Suscreen ?


Winter vs summer

Winter vs summer


Nb uvb vs bb uvb

NB UVB vs BB UVB ?


Materials and methods

Diet ?


Screening

Screening ?


Deficiency

Deficiency ?


Materials and methods

-Vitamin D deficiency is defined as a 25(OH)D below 20 ng/ml (50 nmol/liter)- Vitamin D insufficiency is defined as a 25(OH)D of 21–29 ng/ml


Daily requirement

Daily requirement ?


Treatment

Treatment


  • Login