Inexpensive and accessible thermal imaging for the detection of cancer
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Inexpensive and Accessible Thermal Imaging for the Detection of Cancer. INFRANOSTICS. Angela Fan Ben Wang Mark Bucklin Nancy Diao Olufunke Laseinde. Methods Used to Screen and Monitor for Cancer. A Problem and a Solution. A Device That Will:. Current Methods.

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Inexpensive and Accessible Thermal Imaging for the Detection of Cancer

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Inexpensive and Accessible Thermal Imaging for the Detection of Cancer

INFRANOSTICS

Angela Fan

Ben Wang

Mark Bucklin

Nancy Diao

OlufunkeLaseinde


  • Methods Used to Screen and Monitor for Cancer

A Problem and a Solution

  • A Device That Will:

  • Current Methods

  • Measure Skin-Surface Temperature

  • Expensive

  • Report Topographic Location

  • Uncomfortable

  • Be Inexpensive

  • Inconvenient

  • Software That Will:

  • Rely on Presence of Tumor not Growth of Tumor

  • Map and Record Spatial Temperature Fluctuations

  • Recognize Patterns of Carcinoma Development


  • Common

Detecting Cancer: Current Methods

  • Mammography

  • Self Exam

  • Ultrasound

  • Less Common

  • MRI

  • PET/CT

  • Thermography

From top left, clockwise: Mammogram (Harvey), Breast Self Exam, Ultrasound of the breast (Tiefenbacher), MRI of the breast with T1 contrast and fat reduction (Harvery), Combined PET and CT (Lavayssiere), Breast Thermogram (http://www.aathermography.com)


  • CMOS Focal Plane Array Cameras

Thermography

  • ~10 μm IR radiation at 36º C

  • FDA Approved for Screening Alongside Mammograms

  • Particularly good at screening for

    • Breast Cancer

    • Pain

    • Neurological Disorders

Top to Bottom: Angiogenesis (http://www.gene.com/gene/research/focusareas/oncology/angiogenesis.html), Breast Thermogram (http://www.thermogramcenter.com/Images.htm)


Similar Devices

Handheld Optical Scanner

Thermal Imaging Camera

Single-Sensor Thermography System

  • Near Infrared Absorbance

  • Drexel/Upenn

  • In Clinical Trials

Left: Material from Drexel/Upenn device by Chance, B (http://www.biomed.drexel.edu/new04/Content/ProgressReport/fnir_breastcancer.pdf) , Center:Nec TS9100 Thermal Imaging Camera (www.metrum.co.uk) , Thermal Body Scan (http://thermalbodyscan.com/DITI.aspx). Right: Se Jin Yoon, et. Al. A Study of Thermographic Diagnosis System and Imaging Algorithm

by Distributed Thermal Data using Single Infrared Sensor. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:3319-22.


Design Specifications/Constraints

Versatile

-Comfortable and Adaptable

Power

-Enough power to run a

complete body scan

Design

Specifications/

Constraints

Spatially Accurate

-Develop Anatomically Relevant Temperature Map

Reliable

-At least 95% accuracy

-Detect temperature

changes of ~0.1˚F

Software

-User Friendly GUI

-Pattern Recognition

Accessible/Inexpensive

-Lightweight & Handheld

-Home

-Family Physician,

-Humanitarian


Components and Related Products

Position Tracking

Temperature Measurement

Accelerometer

Gyro

Thermopile

Optical Sensor

Thermistor

Optical Sensor


Design Concept #1

Handheld Device

  • Thermopiles

  • Optoelectronic Sensors

  • Gyro/Accelerometer

  • IR Tracker

CPU

  • Process position

  • Display Coverage

  • Store Temperature

  • Give Directions

  • Diagnose via Pattern Recognition

User

Designed with help from: http://gfx-3d-model.blogspot.com/2008/06/laptop-01.htmlhttp://www.linkwitzlab.com/Pluto/w-asp-pcb.jpg


Design Concept #2

  • Advantages

    • Form-fitting, stationary devices allows the surveyed area to be easily mapped

    • User will be familiar with and the device form

    • Material will be comfortable.

  • Disadvantages

    • Needs to be made for a variety of breast sizes.

Designed with help from: http://gfx-3d-model.blogspot.com/2008/06/laptop-01.htmlhttp://www.linkwitzlab.com/Pluto/w-asp-pcb.jpg


Design Concept #3

  • Advantages

    • No complex tracking needed since device would be stationary

    • Flexible material is suitable for a range of breast sizes

  • Disadvantages

    • May be large, and unwieldy

    • May be uncomfortable


Questions?


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