Oxidative
This presentation is the property of its rightful owner.
Sponsored Links
1 / 35

Oxidative phosphorylation Biochemistry, 4 th edition, RH Garrett & CM Grisham, PowerPoint PPT Presentation


  • 228 Views
  • Uploaded on
  • Presentation posted in: General

Oxidative phosphorylation Biochemistry, 4 th edition, RH Garrett & CM Grisham, Brooks/Cole ( Cengage ); Boston, MA: 2010 pp 592-629 Instructor: Kirill Popov. The mitochondrion Electron transport Oxidative phosphorylation Heat, oxidative stress, etc .

Download Presentation

Oxidative phosphorylation Biochemistry, 4 th edition, RH Garrett & CM Grisham,

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


Oxidative phosphorylation biochemistry 4 th edition rh garrett cm grisham

Oxidative phosphorylation

Biochemistry, 4th edition, RH Garrett & CM Grisham,

Brooks/Cole (Cengage); Boston, MA: 2010

pp 592-629

Instructor: Kirill Popov


Oxidative phosphorylation biochemistry 4 th edition rh garrett cm grisham

The mitochondrion

Electron transport

Oxidative phosphorylation

Heat, oxidative stress, etc.


Oxidative phosphorylation biochemistry 4 th edition rh garrett cm grisham

*Numbers of subunits in the bacterial equivalents in parentheses.

#Cytochromec is not part of an enzyme complex; it moves between Complexes III and IV as a freely soluble protein.


Oxidative phosphorylation biochemistry 4 th edition rh garrett cm grisham

The P/O ratio is an index of the efficiency of coupling

P/O ratio: number of molecules of Pi incorporated (=ATP synthesized) per

atom of oxygen consumed (or pair of electrons being carried through the chain).

Measurements: oxygen consumption during complete phosphorylation

of a fixed amount of ADP after addition of either an NAD+-linked substrate or FAD-linked substrate.

P/O  2.5 for NADH

P/O  1.5 for FADH2


Oxidative phosphorylation biochemistry 4 th edition rh garrett cm grisham

*The number depends on which shuttle system transfers reducing equivalents into the mitochondrion.


  • Login