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B2 Cell Division

B2 Cell Division. Contents. Eukaryotic cell cycle Mitosis and cytokinesis .[,saitəukai'ni:sis] Regulation of the cell cycle. 1. Eukaryotic cell cycle. Cell cycle: the periods between two consecutive divisions, divided into G1, S, G2 and M phases. 6.1 细胞周期（ cell cycle ）.

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B2 Cell Division

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  1. B2 Cell Division

  2. Contents Eukaryotic cell cycle Mitosis and cytokinesis .[,saitəukai'ni:sis] Regulation of the cell cycle

  3. 1. Eukaryotic cell cycle Cell cycle: the periods between two consecutive divisions, divided into G1, S, G2 and M phases

  4. 6.1 细胞周期（cell cycle）

  5. Mitosis and cytokinesis Fluorescence activated cell sorters (FACS) can identify cells of different phases by using an analogs of thymidine

  6. 2. Mitosis and cytokinesis Interphase and mitosis Prophase, metaphase, anaphase, telophase Chromosome: chromatid Daughter chromosome Cleavage furrow and cytokinesis

  7. 一个培养的人类典型细胞各阶段的时间(The time spent in each phase of one complete cell cycle of a human cell in culture )

  8. 6.2 有丝分裂过程图解（以4条染色体为例） Mitosis in an animal cell with a diploid number of 4.

  9. Light micrographs illustrating the stages of mitosis

  10. 6.3 减数分裂（meiosis）

  11. 动物细胞的减数分裂过程 The major events in meiosis in an animal with a diploid number of 4

  12. 动物细胞减数分裂过程（接上图）

  13. Spermatogenesis [,spə:mətəu'dʒenisis] and oogenesis [,əuə'dʒenisis] in animal cells

  14. 3. Regulation of cell cycle Refers to the rate at which cells transverse the cell cycle G0 phase: quiescent cells that require stimulation; specific hormonal growth factors trigger the cells to leave G0 and move through G1 phase

  15. Restriction point, a specific point that regulate cell division

  16. Progress through the cell cycle is mediated by signal transduction and regulated by a series of checkpoints Checkpoints: the cell cannot pass until certain criteria have been fulfilled. Cyclins and cyclin dependent kinases (cdks)

  17. Checkpoints : • the boundary between G1 and S • the boundary between G2 and mitosis • within mitosis • Oncogenes: genes involved in the signal transduction pathway of cell cycle • Tumor suppressor gene: genes involved in the checkpoints

  18. Questions Cell cycle, restriction point, checkpoint, cytokinesis

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