Anatomy physiology and pathology of the lung
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Anatomy, Physiology and Pathology of the lung. The heart and lung block. Airway Anatomy. Human Lung. Anatomy. Lobes. Bronchopulmonary Segments. Alveolus. Type 1 and Type 11 cells. Surfactant. Physiology. Air in and Air out Gas exchange Saturations Alveolar-arterial gradient

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Anatomy, Physiology and Pathology of the lung

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Anatomy physiology and pathology of the lung

Anatomy, Physiology and Pathology of the lung


The heart and lung block

The heart and lung block


Airway anatomy

Airway Anatomy


Human lung

Human Lung


Anatomy

Anatomy


Lobes

Lobes


Bronchopulmonary segments

Bronchopulmonary Segments


Alveolus

Alveolus


Type 1 and type 11 cells

Type 1 and Type 11 cells


Surfactant

Surfactant


Physiology

Physiology

  • Air in and Air out

  • Gas exchange

    • Saturations

    • Alveolar-arterial gradient

  • Metabolic

    • Angiotensin 1 to 2 conversion

    • Eicosanoid metabolism


Gas in and out

Gas in and out


Peak flow

Peak Flow


Volume time

Volume Time


Flow volume loop

Flow Volume Loop


Pathology

Pathology

  • Think Anatomy

  • Trachea

  • Bronchus

  • Alveolus

    • Endothelium

    • Interstitial space

    • Blood vessels

  • COPD

  • Respiratory Failure

  • O2 and oxygen therapy


Tracheal pathology

Tracheal Pathology


Bronchus pathology

Bronchus Pathology


Anatomy physiology and pathology of the lung

COPD

  • Pink puffer or Blue Blotter


Fvc fev1 ratio

FVC/FEV1 ratio


Respiratory failure

Respiratory Failure

  • Respiratory failure is present if PaO2 is less than 8 kPa - 60 mmHg.

  • It is sub-classified into one of two types of respiratory failure based on the level of PaCO2:

  • Type 1 respiratory failure:

    • PaCO2 is less than 6.5 kPa

    • PaO2 less than 8 kPa

  • Type 2 respiratory failure:

    • PaCO2 is greater than 6.5 kPa

    • PaO2 is less than 8 kPa


O 2 and oxygen therapy

O2 and oxygen therapy

  • Patients with chronic hypoxia from chronic lung disease

  • Poor PaO2 and good sats

  • Acute unwell hypoxic patients need 100% oxygen


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