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制剂与处方. 主讲: 黄红林. 制剂与处方. 第一节 药典与药物剂型简介 第二节 处方学 第三节 小儿剂量的计算. 第一节 药典与药物剂型简介 一、药典   药典 (Pharmacopoeia) 是一个国家药品规格标准的 法典 。由国家编撰,并由政府颁布施行,具有 法律性 的约束力,药典收载功效确切,副作用较小,质量较稳定的常用药物和制剂,并规定其质量标准制备要求,检验方法,作用与用途、用法和用量等,以作为药品生产,检验和使用的依据。. 《 中华人民共和国药典 》 与主要国外药典.

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制剂与处方

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4757114

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(Pharmacopoeia)

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Chinese Pharmacopoeia ,ChP 20001953196319771985199019952000 19951997 1998,

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(1) (8)

(9)

(2) (10)

(3) (11)

(4) (12)

(13)

(5) (14)

(6) (15)

(7)

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242000(The United PharmacopoeiaUSP)

19(the national FormularyNF) USP(24)-NF(19)

1998,British PharmacopoeiaBP(1998)

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14JP(14)

3

(European PharmacopoeiaPh.Eup)

3

(The International Pharmacopoeia,Ph.Int)

197719811998

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()1LiquiedSol.

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2(TincturaTr.) 10%20%(100ml20) ()

()1550%

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3 mistura mist

3(Mistura, Mist.)

4(Syrupus, syr.)()

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5(Injection, Amp) ()()100ml)

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  • 1.1

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  • 1.2

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  • (1) pH

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(2) 1251020()()l:0.51:12:10!

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(3pHpH(20)pH2.510.55.08.0

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(4) (20)

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6(Suspensionsusp.) ,7(Liquid extract Liq.ext.)1

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8 decoction dec 9 lotion lot

8(DecoctionDec),9(LotionLot)

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1 unguentum ung

()1(UnguentumUng)

(Oculentum Occul) (50um)

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2(PlastumPlast.)

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3(Extract Extr.)25 4PasturaPast

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1 granula gran

()1(Granula, Gran) ,,

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2(Tabella Tab.) :(1)(2)

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:(1):()()(2):

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3 4 5

(3)(4) (5)

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3 rilulla pil 100 ad

3(Rilulla, pil) (100)AD

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4 suppositorium supp

4(Suppositorium, supp)

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5(Capsula, caps) 6(Prlvis Pulv)

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7(Membrana Menbr) ()(Filmun Film.)

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Aerosolum

(Aerosolum)

()(Inhaltion)(Nebula)

(Tumcgantum)

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1. (microcapsule)

5400umA

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2. (liposomes)

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B

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3. (Magnetic microspheres)

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4. (pro-drug preparations)

()()

()

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  • 5-FU

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5.(sheet)

:()()()()

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:1:,2:RpRRecipe 3:4:5:()SigS6:

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1 23

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45067Cito()

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8(g)(ml)gmlmg()U()9

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g gtt. mgg(mcg)mlu

L

Kg

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Amp. Mist.(Mixt) Caps. Sol.Liq. Extr. Ung. Syr. Ocul. Tab. Supp. Tr. Pil. Inj. Pulv. Lot. Loz. Past. Emui.

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a.c. q.o.d. p.c. q.d. a.m. q.i.d p.m. q.4h.4q.m. q.8h. 8q.n. h.s. b.i.d. S.O.S. t.i.d. p.r.n. st. () Cito!

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i.m. i.v. p.o. Pr. ocul. p.rect. Pr.aur. i.h.(H) Pr.nar. i.d. A.S.T.(H.test.) i.v.gtt.i.v.drip.

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q.s. Co. aa. ad. Aq.dest. et. No. prim.vic. Sig.S. mixt. lent.

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1

________ _____

Rp.

Inj. Penicilli.G 80u*6

Sig. 80u i.m. Bid (HT!)

____

____

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2

______________

Rp.

Tab. Aspirin 0.3*3

Sig. 0.3 tid

Cap. Captoprin 25mg*30

Sig. 25mg tid

____

____

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()1:()()()

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Rp ()

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1()Rp Tab. Aspirini 0.510 Sig. 0.5 t.i.d. 2()Rp Caps. Tetracyclini 0.2516 Sig. 0.25 q.6h.

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3 rp inj penicillini g 80 u 4 sig 80 u i m b i d a s t

3()Rp Inj. Penicillini G 80u4 Sig. 80u i.m. b.i.d. A.S.T.

Rp

G 80u4

80u2

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4 rp tab vit b co 100 sig 2 t i d

()((#))4()Rp Tab. Vit. B Co. 100 # Sig. 2# t.i.d.

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2:()()

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:

Rp(%)

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5()Rp Liq. Ammonii Chloridi 10100.0 Sig. 10.0 t.i.d.6()Rp Ung. Zinci Oxydi 1010.0 Sig. qs. ext.

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7()Rp Syr. Ferri Ammonii Citratis 100.0 Sig. 10.0 t.i.d.8()Rp Mist. Pepsini 100.0 Sig. 10.0 t.i.d. a.c.

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9()Rp Guttae Chloramphenicoli 0.2520.0 Sig. q.i.d. Pr. ocul.

10()Rp Inj. Aminophyllini 0.251 Inj. Glucosi 50%20.0 Sig. mixt.i.v. lent.

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11()Rp Inj. Penicillini G Natrici 400,000u4 Sig. 400,000u i.m. b.i.d. A.S.T. Tab. Trimethoprime 0.18# Sig. 0.2 b.i.d. Tab. APC 8# Sig. 1# S.O.S. Mist. Glyccyrrhizae Co. 100.0 Sig. 10.0 t.i.d.

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mg/kg/d

=X 2 Xkg/100

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16

kg= 0.6+3

712

kg=-60.5+6 0.6+ 3

1

kg= 2+8

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12()

0.5mg/kg/712.5mg/ 1ml25mgml

=7 2+8=22kg

=22 0.5mg=11mg1

251=11V

V=11/25=0.44ml

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18Sinomini Co.5-10ml

Rp Syr. Sinomini Co. 18.0 Sig. 3.0 b.i.d.=8 2+8=24kg

[24kg 5(10)/50=2.44.8ml]

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2Sulfadiaziui1g4Natrii Bicarbonatis0.5g/

Rp Tab. Sulfadiaziui 0.526 Tab. Natrii Bicarbonatis 0.526

Sig. aa. 2.0, prim. vic. 1.0 q.i.d.

Rp

0.526

0.526

1.04

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Thank you !!

June 2005

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