slide1
Download
Skip this Video
Download Presentation
Indications Cystitis after radiotherapy for prostatic cancer

Loading in 2 Seconds...

play fullscreen
1 / 7

Indications Cystitis after radiotherapy for prostatic cancer - PowerPoint PPT Presentation


  • 114 Views
  • Uploaded on

Efficacy of sodium hyaluronate in the management of chemical and radiation cystitis Sommariva et al. Minerrva Urol Nefrol 2010. Indications Cystitis after radiotherapy for prostatic cancer

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about ' Indications Cystitis after radiotherapy for prostatic cancer' - lolita


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
slide1

Efficacy of sodiumhyaluronate in themanagement of chemical and radiationcystitisSommariva et al.

MinerrvaUrolNefrol 2010

slide2

Indications

  • Cystitisafterradiotherapyforprostaticcancer
  • Cystitis in patientsreceivinginmuno-chemotherapeuticagentsbyintravesicalinjstillationfor non-muscleinvasivetransitionalcell carcinoma of thebladder (BCG orMitomycin C)

Poor and Slow response tothe usual symptomatictreatments

Thesebladdersymptomsoften mean thatcancertherapy has tobeinterrupted, which has furtherclinicalimplications, liketheimpactonthepossibility of success

slide3

Administration of Cystistat

  • 69 maleconsecutivepatients
  • 15 afterRadiotherapy (Rxt)
  • 24 after BCG
  • 30afterMitomycin C
slide4

Administration of Cystistat

  • Cystistatwasadministeredweeklyfrom 8 to 24 weeks, dependingonhowthyesymptomsreleased.
  • Lidocaine 2% 30 mLwasinstilled 30 min before, toallowpatientstokeepCystistatwithinthebladder
  • In thefirst 4 weeks, Dexamethasone 32 mg wasmixedto HA lookingforanantiinflammatoryeffect
slide5

Results

  • – BladderCapacity (BC)
  • – Visual Analogic Score (VAS) forPain
  • Afteronly 4 weeks BC increased in allpatients, and Urgency and Painalmostdisappeared. Treatmentwascontinuedhoweverforanother 4 weeks, even in patientswith total remission of theirsymptoms.
  • Itwasseenpreviouslybytheauthorsthatiftherapystoppedtosoon, thenthesymptomscouldreturn.
slide6

ChemicalCystitisgroupRIC groupBTATBTAT

VAS 8,6 0,9 NotMeasured

  • (Frequency + Urgency)
  • BC BTATBTAT
  • 58,4 283,7 85,0243,3
slide7

97% reported complete relief of dysuria and pain

  • No adversereactions, allowingtheconclusion of treatmentsforbladdercancer
  • Aftertherapy, urinarycitology and cistoscopyruledoutbledderrcancerprogression
  • Conclusion:
  • IntravesicalHyaluronan (HA) seems a valid and quicktherapeuticsolutionforiatrogeniccystitisfromchemoorradiotherapy
ad