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Nurse-Led Investigation of the Relationship Between Dietary Fiber and Crohn's Disease Symptoms. 2013 Advances in Inflammatory Bowel Diseases Hollywood, Florida December 12, 2013 Carol S. Brotherton, PhD, MSN, RN George Mason University, Fairfax, Virginia. Disclosures. Nothing to Disclose.
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Nurse-Led Investigation of the Relationship Between Dietary Fiber and Crohn's Disease Symptoms 2013 Advances in Inflammatory Bowel Diseases Hollywood, Florida December 12, 2013 Carol S. Brotherton, PhD, MSN, RN George Mason University, Fairfax, Virginia
Disclosures Nothing to Disclose
My background… Family and community experiences (beginning in 1977) Some people with Crohn’s disease can control their symptoms through therapeutic use of dietary fiber Clinical nursing in gastroenterology/outpatient surgery settings (1992 - 2007) • Benefits of dietary fiber are not taught in conventional Crohn’s disease care • Patients can be taught about the benefits of fiber and observe improvements similar to that of individuals in the community NIH-funded researcher (2008 – present) Research program focused on lifestyle factors that affect CD symptoms
Contraindications… • Recent surgery • Obstructive strictures • Open fistulas • Short bowel syndrome • Wheat allergy/gluten intolerance/celiac disease
What I taught… • Epidemiology evidence • Fiber effects in the GI tract • Fiber heterogeneity • Anecdotal evidence • Label reading
What we did… • Design: 4-week, 2-group, single-blind, randomized, controlled • Purpose: to investigate the effects of fiber-related dietary instructions specifying wheat bran consumption on GI symptoms and HQoL in individuals diagnosed with CD Independent Variable Dependent Variables
What we found… No group differences at baseline
What we found… Partial Harvey Bradshaw Index (pHBI) Lower Scores=Diminished Symptoms Groups Bran treatment Control Repeated Measures ANOVA P = 0.008
What we found… Inflammatory Bowel Disease Questionnaire (IBDQ) Higher Scores=Better Quality of Life Groups Bran treatment Control Repeated Measures ANOVA P = 0.028
Conclusions… Limitations • Small sample size • Limited generalizability • Limited power for objective measures Implications Disconnect between research and practice Patients with Crohn’s disease may benefit from receiving information from nurses about the effects of dietary fiber in the gastrointestinal tract Future Research • Test intervention in a larger, more diverse sample • Choose outcomes and measures that are not affected by biologic drugs (effect of fiber on microbiota?)
Thank you! Questions? Email: cbrothe2@gmu.edu