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Version 10. Mission; Foster adoption of…. pragmatic and cost effective standards for accurate and reproducible longitudinal quantitation of biologic parameters with clinical relevance and known sigma. H/o Commercial Dx Individuals - thresholds Categorical, staging Workflow/# studies

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Presentation Transcript

Mission foster adoption of
Mission; Foster adoption of…

  • pragmatic and cost effective standards for

  • accurate and reproducible

  • longitudinal

  • quantitation of

  • biologic parameters

  • with clinical relevance

  • and known sigma


Monitoring rx benefit individualized medicine convergence of biomarkers and diagnostics

H/o Commercial Dx

Individuals - thresholds

Categorical, staging

Workflow/# studies

Binary – choice of Rx

Biomarkers become Dx

Populations – means

Continuous, quantitative

Automation/bias

Longitudinal – Rx effect

Monitoring Rx Benefit = Individualized MedicineConvergence of Biomarkers and Diagnostics

Quantifying the effects of drugs in development

may beg access to biomarkers as diagnostics


Milestone horizon pet ct

RSNA ’10 and on

Milestone horizon/PET-CT

RSNA ‘09

Calibration Phantoms

Characterization Lo, Hi rads

RoI Definition*

Dynamic Range lesion size**

RSNA ‘08

Interoperability of

Results Encoding

Image Quality Metrics

Quantitation Computation

Documentation of terms

High

High

High

High

Medium

High

Value

H, M, L

High

High

High

High

High

Feasibility

H, M, L

High

*Adoption 2010-11, but Define by 2008

Priority

H, M, L

N/A

Quick Hits

**Ideal Phantom 2010-11 Current phantom by 2008

Chair

H, M, L

TBN

Clunie



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