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NCI Funding Opportunities in Health Services and Outcomes Research Steven B. Clauser, Ph.D.

NCI Funding Opportunities in Health Services and Outcomes Research Steven B. Clauser, Ph.D. Chief, Outcomes Research Branch Applied Research Program Division of Cancer Control and Population Sciences http://appliedresearch.cancer.gov/ Academy Health Annual Meeting

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NCI Funding Opportunities in Health Services and Outcomes Research Steven B. Clauser, Ph.D.

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  1. NCI Funding Opportunities in Health Services and Outcomes Research Steven B. Clauser, Ph.D. Chief, Outcomes Research Branch Applied Research Program Division of Cancer Control and Population Sciences http://appliedresearch.cancer.gov/ Academy Health Annual Meeting Washington, DC June 9, 2008

  2. Session Outline • Who We Are and What We Do • Organizational contacts and expertise • HSR priority areas related to key branch missions • NCI Research Resources for Health Services and Outcomes Research Investigators • NCI Funding for HSR-related research • Potential research resources and consortia connections for extramural investigators • Funding Opportunities for Junior and Mid-level Investigators

  3. DCCPS ORGANIZATION CHART Office of the Director Dr. Robert T. Croyle, Director Office ofCancer Survivorship Dr. Julia H. Rowland Epidemiology andGenetics ResearchProgram Dr. Deborah Winn (Acting) Behavioral Research Program Dr. Robert T. Croyle (Acting) Applied Research Program Dr. Rachel Ballard-Barbash Surveillance Research Program Dr. Brenda K. Edwards Applied CancerScreening Research Dr. Steve Taplin (Acting) Health Services and Economics Dr. Martin Brown Cancer Statistics Mr. David Stinchcomb Methods and Technologies Branch Dr. Mukesh Verma Basic and BiobehavioralResearch Dr. Paige McDonald Statistical Research and Applications Dr. Eric Feuer OutcomesResearch Dr. Steven Clauser Modifiable Risk Factors Dr. Britt Reid Health Communicationand Informatics Research Dr. Bradford Hesse Risk Factor Monitoring and Methods Dr. Susan Krebs-Smith Host Susceptibility Dr. Mukesh Verma (Acting) Health PromotionResearch Dr. Linda Nebeling Clinical and Translational Epidemiology Dr. Deborah Winn (Acting) Tobacco ControlResearch Dr. Cathy Backinger Revised 5/08

  4. HealthServices Research Energy Balance and Cancer Cancer Screening Quality/Patterns of Care Outcomes Measurement ARP STAFF EXPERTISE Risk Modeling Health Disparities Genetics and Family History Cost-Effectiveness Analysis Diet, Physical Activity, Tobacco http://appliedresearch.cancer.gov/about/staff/

  5. Health Services and Economics Branch The Branch’s mission: • Support, conduct, and coordinate research on the dissemination of effective cancer-related health services into community practice. • Study demographic, social, economic, and health system factors as they relate to providing preventive, screening, diagnostic, and treatment services for cancer. • Improve cancer outcomes, reduce cancer-related health disparities, and reduce the burden of cancer to patients, their families, and society.

  6. HSEB carries out its mission by…. • Monitoring cancer-related health services utilization and outcomes among individuals in the general population and among selected population subgroups; • Monitoring the dissemination and effective delivery of cancer-related health services by community-based health care providers and health care delivery organizations; • Assessing the role of economic factors related to the equitable, efficient, and effective provision of cancer-related health services; • developing and disseminating data resources to support policy-relevant research http://healthservices.cancer.gov/about/

  7. Outcomes Research Branch The Branch mission: • Coordinate and sponsor research to measure, evaluate, and improve patient-centered outcomes of cancer care delivery across the cancer care continuum. • ORB is particularly interested in morbidity and mortality outcomes, patient symptoms and health-related quality of life, and patient experience of and satisfaction with health care.

  8. ORB carries out it’s mission by…. • Enhancing the state of the science of outcomes measurement, especially patient-reported outcomes; • Assessing, monitoring, and enhancing patient-centered cancer care at all levels -- the provider-patient interaction, the health care organization, and the health care system; • Translating research findings into care delivery products and strategies for use by public and private decision makers, who provide, pay for, regulate, set standards for, and make personal decisions about cancer care; and • Evaluating innovative programs designed to improve the effectiveness and efficiency of providing evidence-based practice throughout the cancer care continuum. http://outcomes.cancer.gov/

  9. Health Services/Outcomes Research is Relevant Across the Cancer Continuum Diagnosis Detection Treatment Prevention Survivorship • Cancer Screening Recommenda-tions and Practices • Risk Assessment (Cancer genetics) • Timely Diagnosis and Referral • Obesity diagnosis and management • Risk Assessment Communication/ • Counseling • Cancer chemo- prevention • End-of-Life Care • Use of Evidence- • Based Therapies • Pain Management • Follow-up of cancer survivors • Cross Cutting Topics • Access to Care • Health Disparities • Economics of Cancer Care • Quality of Care • Quality of Life/Patient Centered Care

  10. DCCPS Source of Funding and Expenditures (FY07) Collaborations RPG Cancer Control FundingSources DCCPS In-house 6% Expenditures Investigator Initiated 49% IAA/MOU Contracts 13% RFA/PA 32%

  11. Distribution of ARP Funding Related to Health Services/Outcomes Research in 2007

  12. ARP Health Services/Outcomes Related Grant Funding, 1998-2007

  13. NCI Health Service Research Resources Building Infrastructure for Extramural Investigators

  14. Data Resources for Investigators • Cancer Registry Based Resources • SEER • Patterns of Care/Quality of Care Studies • SEER-Medicare Linked Databases • Consumer and Healthcare Provider Surveys • National Health Interview Survey Cancer Control Module • California Health Interview Survey • National Survey of Colorectal Cancer Screening Practices – 2000, 2006 • Public Health Research Resources • Cancer Planet • Outcomes Research Resources • PROMIS Quality of Life Measures and CAT applications

  15. Use of PSA testing, mammography, sigmoidoscopy/ colonoscopy Patterns of care Peri-operative complications Volume outcomes studies Comorbidities Health disparities Late effects of treatment Post-diagnostic surveillance Treatment of prevalent cancers Survival Rates of recurrence/ second primaries Relationship of second events to initial treatment and ongoing surveillance Use of hospice End-of-life patterns of care Example:SEER-Medicare Data Are Useful for Research Across the Cancer Continuum Screening/ Diagnosis/ Survivorship Secondary  Terminal CareDetection & TreatmentOccurrence Over 150 SEER-Medicare articles in print

  16. http://www.nihpromis.org pain fatigue emotional distress physicalfunction Domain definitions item content review item characteristics social roleparticipation Example:PROMIS Measure Website What would you like to measure in your study? Click below for: or select a box on the right and proceed

  17. NCI Health Services Research Networks • National, multi-site research networks that • Can enroll large cohorts of individuals • Track receipt of cancer control services longitudinally at the patient, provider, and health system levels • Investigate impact of interventions on patient-centered outcomes • Current Examples • Breast Cancer Surveillance Consortium (BCSC) • Cancer Research Network (CRN) • Cancer Care Outcomes Research and Surveillance Consortium (CanCORS)

  18. NCI Consortium-based Research Platforms Breast Cancer Surveillance Consortium Cancer Research Network

  19. $$$$$$$$$$$ Health Services/Outcomes Research Funding Opportunities at NCl

  20. NCI Funding Mechanisms for Junior and Mid-level Investigators • K-Awards – NCI Training Awards • R03 – Small Research Grants in Behavioral and Social Sciences • R21 – Exploratory/Developmental Grants • R01 – Research Projects • http://deainfo.nci.nih.gov/flash/awards.htm • General Grant Applications Instructions • http://deainfo.nci.nih.gov/flash/awards.htm

  21. Current Health Services Research Program Announcements • PA-02-005: Economic Studies in Cancer Prevention, Screening and Care(R01, R21) http://grants.nih.gov/grants/guide/pa-files/PA-02-005.html • PA-02-006: Cancer Surveillance Using Health Claims-Based Data System(R01, R21) http://grants.nih.gov/grants/guide/pa-files/PA-02-006.html • PA-02-015: Enhanced Understanding of Colorectal Cancer Screening(R21) http://grants.nih.gov/grants/guide/pa-files/PA-02-015.html • PA-05-090: Methodology and Measurement in the Behavioral and Social Sciences(R01, R21) http://grants1.nih.gov/grants/guide/pa-files/PA-05-090.html

  22. NCI Funding Mechanisms for Dissemination and Implementation Research • R03 – Small Research Grants • Dissemination and Implementation Research in Health • http://grants2.nih.gov/grants/guide/pa-files/PAR-06-071.html • R21 – Exploratory/Developmental Grants • Dissemination and Implementation Research in Health • http://grants2.nih.gov/grants/guide/pa-files/PAR-06-072.html • R01 – Research Projects • Dissemination and Implementation Research in Health • http://grants1.nih.gov/grants/guide/pa-files/PAR-06-039.html

  23. For further information on anything presented today -- including most appropriate NCI contacts, email …. Steven Clauser, Ph.D. Chief, Outcomes Research Branch Clausers@mail.nih.gov Martin Brown, Ph.D. Chief, Health Services & Economics Branch Brownm@mail.nih.gov

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