A Closer Look at the Blood Group Systems: An IRL’s Point of View. Jennifer Haywood, MLS(ASCP)SBB Regional Transfusion Services Coordinator Omega Diagnostics, LLC Shreveport, LA. Objectives. List and describe antigens of the major blood group systems
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A Closer Look at the Blood Group Systems:An IRL’s Point of View
Jennifer Haywood, MLS(ASCP)SBB
Regional Transfusion Services Coordinator
Omega Diagnostics, LLC
Immunohematology Reference Laboratories:
highly specialized laboratory that provides an essential service to patients who have specific serologic complexities and/or need rare blood components.
provide an exchange of information and consultation on rare blood group antibodies, component preparation and therapy, blood compatibility testing and research.
3. low incidence antigens (700 series)
4. high incidence antigens (901 series)
Table of blood group systems
ISBT Human Blood Group Systems
(Fy4 is now obsolete)
JK locus (found in polynesians)
2. dominant inhibitor gene In(Jk)
(found in Japanese)
“Characterization of Jk(a+weak): a new blood group phenotype associated with an altered JK*01 allele”
P1 and P2 phenotypes account for >99% of population. Both synthesize Pk and P antigens.
3 rare phenoypes:
- Also suppresses P1, AnWj