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Australian Wagyu Society. Geelong October 11, 2013. About GeneSeek. Started in 1998 with one student intern Vision: Affordable, flexible DNA Analysis for agribusiness Now 18 30 43 70 FTE (and many robots) Began 600 sqft , currently 3000 4000 8000 12000

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Australian wagyu society

Australian Wagyu Society

Geelong

October 11, 2013


About GeneSeek

  • Started in 1998 with one student intern

  • Vision: Affordable, flexible DNA Analysis for agribusiness

  • Now18 3043 70 FTE (and many robots)

  • Began 600 sqft, currently 3000 40008000 12000

  • Acquired by Neogen in 2010

  • >700,000 samples this year


Genomic Solutions

Custom Content

HD SNP

Profiling

Sample

Management

Identity &

Diagnostics

Project Management

Tissue/Hair

Samples

Sequenom

Low SNP

Sequenom

SNP Panels

Affymetrix

GeneTitan

Contract

R&D

Illumina

I-Select

Illumina

Infinium

qPCR

Microsatellites

Consultation

ELISA

DNA

Rigorous Quality Control


P rimary t echnology p latforms
Primary Technology Platforms

  • Illumina I-Scan - AffymetrixGeneTitan

    • Higher density SNP profiling (384-1,000,000+)

  • SequenomMassARRAY

    • Lower volume SNP panels (1-384) marker assisted selection and Identity Management

  • DNA Sequencers

    • Microsatellite panels for identity management and single gene tests for selection and disease management. MySeq for sequence analysis

  • ELISA and Real-time PCR

    • Pathogen detection for disease management



  • One Sample, One Stop: Many answers

    SNP Chips - Informational Powerhouses


    One Sample, One Stop: Many answers

    SNP Chips - Informational Powerhouses

    Coat Color

    AM

    Fertility

    markers

    Milk Quality

    Parentage

    GGP

    Fawn Calf


    Transforming snp chips into i nformational powerhouses
    Transforming SNP chips into Informational Powerhouses

    ?

    90K



    Dry Matter Intake

    Birth Weight

    Mature Height

    Mature Weight

    Milk

    Scrotal Circumference

    Weaning Weight

    Yearling Weight

    Marbling

    Ribeye Area

    Fat Thickness

    Carcass Weight

    Tenderness

    Percent Choice (quality grade)

    Heifer Pregnancy

    Maternal Calving Ease

    Direct Calving Ease

    Docility

    Average Daily Gain

    Feed Efficiency

    Yearling Height

    Also providing GE-EPDs for

    Limousin

    Red Angus

    Hereford

    Simmental

    More pending


    Bosindicus

    • ~1,700 Nellore

    • ~700 Brahman

    • ~250 Brangus

    GGP

    GGP – Bosindicus

    90K – Bosindicus

    90K

    • Commercial heifer product?

    HD


    Why dna
    Why DNA?

    • Traits that are difficult and/or expensive to measure and have a large economic impact

      • Carcass traits

      • Feed Efficiency

      • Fertility

      • Immune response

      • Tenderness

      • Longevity

    “ Marker-assisted selection has the potential to greatly improve how quickly we can make genetic progress in many traits for which we do and do not currently have EPDs.”

    Dr. Mark Enns, Colorado State University June 2009 Brangus Journal



    Producers in Australia are raising that is very soft.Wagyu cattle to achieve the marbling and soft fat that the Japanese prefer.

    Wally Ray at the Overflow Ranch in north Queensland.


    We tested the effects of different types of ground beef in men
    We tested the effects of that is very soft.different types of ground beef in men.

    MUFA:SFA = 0.93

    MUFA:SFA = 1.25


    Ground beef high in mufa increases hdl good cholesterol in men
    Ground beef high in MUFA that is very soft.increasesHDL (good) cholesterol in men.

    MUFA:SFA = 0.93

    MUFA:SFA = 1.25


    Igenity profile tenderness score wbsf
    IGENITY that is very soft.® Profile Tenderness Score & WBSF

    More Tender

    Shear Force Difference (lb)

    2.3 lb. difference

    IGENITY Profile Tenderness Score

    Data derived from NBCEC Nov. 2005


    Why dna1
    Why DNA? that is very soft.

    • SNP Parentage

      • Added seedstock value

      • Multi-sire pastures

      • Genetic evaluation for commercial cow-calf producers

      • Solve problems


    Snp for parentage and identity
    SNP for parentage and identity that is very soft.

    Sire B

    Sire A

    AT

    AA

    TT

    Calf

    Sire A is “excluded” as the sire at that locus – except in the case of

    a genotyping error


    Why dna2
    Why DNA? that is very soft.

    • Manage genetic defects

    Salvage valuable genetics.


    Why dna3
    Why DNA? that is very soft.

    When combined with performance records, genomic data improved selection response 20% to 41%, depending on the trait1

    1Van Eenennaam, A.L., J.H. van der Werf, and M.E.Goddard. 2010. Value of DNA information for bull selection. 9th World Congress of Genetics Applied to Livestock Production, Leipzip, Germany.


    Sample collection
    Sample Collection that is very soft.


    Endless Possibilities… that is very soft.

    Affordable Custom Chips:

    any snp number, any sample size

    SAME GREAT SERVICE!


    Thank you! that is very soft.


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