Atherosclerotic coronary vascular disease. leading cause of death in the U.S. !! men > 40 y.o. women > 50 y.o. declining rates since 1980 : 42 % !! lifestyle alterations 7-9 million Americans. Atherosclerotic coronary vascular disease. ASYMPTOMATIC ~ 50 % SYMPTOMATIC ~ 50 %
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PLAQUE RUPTURE AND BLOOD CLOTTING IN AN ATHERO-SCLEROTIC BLOOD VESSEL
Red blood cells
Use of HMg COAs can reduce cholesterol by 35%. * Should not be used with
cyclosporine, niacin, gemfibrozil - myositis; however no reports with fluvastatin
“MI”, “Coronary”, “Heart Attack”
Infarction - an area of necrosis in tissue due to ischemia resulting from obstruction of blood flow