Dynamic Programming. How to match up sequences and have the matches make sense and be quantitative. Question is. How does a specific sequence compare to one other specific sequence? Is it similar? If so, at what level? Can’t compare every base to every other base--to complex.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
How to match up sequences and have the matches make sense and be quantitative
(Could have others; could choose different values)
Homologous sequences (homologues)
Share a common ancestor
Homologues derived by gene duplication
Functions may vary
Look for differences
Homologues derived by speciation
Look for similarities
AMY1 has a three amino acid deletion
Active site residues
Variation in the active site loop among plant and bacterial -amylases