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PROTEIN PHYSICS LECTURE 7

PROTEIN PHYSICS LECTURE 7. Main secondary structures. H-bonds. Helices: Right and Left. Mirror-asymmetric amino acids – mirror-asymmetric (“chiral”) helices Right -helix. Right  -helix. Right -helix Right 3 10 helix. ALA, etc. GLY only. , twisted. ,

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PROTEIN PHYSICS LECTURE 7

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  1. PROTEIN PHYSICS LECTURE 7

  2. Main secondary structures

  3. H-bonds Helices: Right and Left

  4. Mirror-asymmetric amino acids – mirror-asymmetric (“chiral”) helices Right -helix

  5. Right -helix

  6. Right -helix Right 310 helix

  7. ALA, etc. GLY only

  8. , twisted

  9. , twisted

  10. Mirror-asymmetric amino acids – mirror-asymmetric twist of -sheets

  11. -hairpin with turn

  12. turn I turn I’ turn II

  13. -bulge

  14. collagen triple helix

  15. Experimental study of secondary structure X-ray crystallography NMR spectroscopy (cross-peaks)

  16. Experimental study of secondary structure Far UV CD spectra (peptide groups) IR spectra (amid I, C=O bond)

  17. Membrane Globular Fibrous H-bonds & hydrophobics

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