1 / 33

PH402

libitha
Download Presentation

PH402

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

    1. PH402 Hypertension and Antihypertensives Chris Hague, PhD chague@u.washington.edu Technical Advisor: Seth Goldenberg, PhD

    2. Brody’s Human Pharmacology, 4th Edition Guyton Human Physiology http://www.americanheart.org/presenter.jhtml?identifier=2152 http://www.nhlbi.nih.gov/health/dci/Diseases/Hbp/HBP_WhatIs.html References

    10. 42,418 participants Findings: Chlorthalidone is superior to an ACE inhibitor, a calcium channel blocker and an alpha1-adrenergic antagonist in preventing one or more CVD events. Recommendations for antihypertensive treatment: Use Thiazide-type diuretics as first treatment in stage I and II hypertension prevent cardiovascular disease better than other classes lower cost drugs of choice for first-step antihypertensive therapy. Diuretic intolerant patients: consider Ca2+ channel blockers and ACE inhibitors Most hypertensive patients require more than one drug. Diuretics should generally be part of the antihypertensive regimen. Lifestyle advice should also be provided. http://www.nhlbi.nih.gov/health/allhat/index.htm

More Related