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ENZYMES. SSME-518 Instructional Technology and Material Development Assignment2 Presented by: Harika Özge Kızılsu. Outline. Introduction to enzymes How enzyme work Activation energy Factors effecting enzyme activity Temperature pH Enzyme concentration

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ENZYMES

SSME-518Instructional Technology and Material Development

Assignment2

Presented by: Harika Özge Kızılsu

H.Özge Kızılsu


Outline
Outline

  • Introduction to enzymes

  • How enzyme work

    • Activation energy

  • Factors effecting enzyme activity

    • Temperature

    • pH

    • Enzyme concentration

    • Substrate concentration

H.Özge Kızılsu


Introduction to enzymes
Introduction to enzymes

  • Enzymes are usually proteins

  • Enzymes are catalysts

    • In general, names end with suffix “ase”

H.Özge Kızılsu


Introduction to enzymes1
Introduction to enzymes

3 x 1012 years is 500 times the age of the earth!!!!

H.Özge Kızılsu


Introduction to enzymes2
Introduction to enzymes

Enzymes:

  • increase the rate of a reaction

  • not consumed by the reaction

  • act repeatedly to increase the rate of reactions

  • are often very “specific” for the substrate

    Reactants also called “substrates” of enzyme

H.Özge Kızılsu


How enzyme work
How enzyme work

  • Enzymes physically interact with their substrates

  • Substrates bind to the enzyme’s active site

  • Enzyme reaction path:

H.Özge Kızılsu


How enzyme work1
How enzyme work

Substrate fits into an active site perfectly.

(key) (lock)

  • Lock and Key Model

click to see animation of model

H.Özge Kızılsu


How enzyme work2
How enzyme work

  • Activation energy is:

    the energy required to start a reaction.

H.Özge Kızılsu


Factors effecting enzyme activity
Factors effecting enzyme activity

  • Temperature

  • pH

  • Enzyme concentration

  • Substrate concentration

H.Özge Kızılsu


Temperature

Temperature

H.Özge Kızılsu


pH

H.Özge Kızılsu


Enzyme concentration

Substrate concentration constant

Enzyme concentration

H.Özge Kızılsu


Substrate concentration
Substrate concentration

click to learn more

Enzyme concentration constant

H.Özge Kızılsu


Thank YOU 

H.Özge Kızılsu


References
References

  • http://fig.cox.miami.edu/~cmallery/255/255enz/enzymology.htm

  • http://ntri.tamuk.edu/cell/enzyme2.html

  • http://www.animationfactory.com/animations/buildings/doors/6038e/

H.Özge Kızılsu


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