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SSME-518 Instructional Technology and Material Development Assignment2

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ENZYMES. SSME-518 Instructional Technology and Material Development Assignment2 Presented by: Harika Özge Kızılsu. Outline. Introduction to enzymes How enzyme work Activation energy Factors effecting enzyme activity Temperature pH Enzyme concentration

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ENZYMES

SSME-518Instructional Technology and Material Development

Assignment2

Presented by: Harika Özge Kızılsu

H.Özge Kızılsu

outline
Outline
  • Introduction to enzymes
  • How enzyme work
    • Activation energy
  • Factors effecting enzyme activity
    • Temperature
    • pH
    • Enzyme concentration
    • Substrate concentration

H.Özge Kızılsu

introduction to enzymes
Introduction to enzymes
  • Enzymes are usually proteins
  • Enzymes are catalysts

• In general, names end with suffix “ase”

H.Özge Kızılsu

introduction to enzymes1
Introduction to enzymes

3 x 1012 years is 500 times the age of the earth!!!!

H.Özge Kızılsu

introduction to enzymes2
Introduction to enzymes

Enzymes:

  • increase the rate of a reaction
  • not consumed by the reaction
  • act repeatedly to increase the rate of reactions
  • are often very “specific” for the substrate

Reactants also called “substrates” of enzyme

H.Özge Kızılsu

how enzyme work
How enzyme work
  • Enzymes physically interact with their substrates
  • Substrates bind to the enzyme’s active site
  • Enzyme reaction path:

H.Özge Kızılsu

how enzyme work1
How enzyme work

Substrate fits into an active site perfectly.

(key) (lock)

  • Lock and Key Model

click to see animation of model

H.Özge Kızılsu

how enzyme work2
How enzyme work
  • Activation energy is:

the energy required to start a reaction.

H.Özge Kızılsu

factors effecting enzyme activity
Factors effecting enzyme activity
  • Temperature
  • pH
  • Enzyme concentration
  • Substrate concentration

H.Özge Kızılsu

slide11
pH

H.Özge Kızılsu

substrate concentration
Substrate concentration

click to learn more

Enzyme concentration constant

H.Özge Kızılsu

slide14
 Thank YOU 

H.Özge Kızılsu

references
References
  • http://fig.cox.miami.edu/~cmallery/255/255enz/enzymology.htm
  • http://ntri.tamuk.edu/cell/enzyme2.html
  • http://www.animationfactory.com/animations/buildings/doors/6038e/

H.Özge Kızılsu

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