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Étude FIRE-3. Résultats selon le statut RAS (KRAS/NRAS exons 2, 3, 4). ESMO 2013 - D’après Stintzing S et al., LBA 17, actualisé. La Lettre du Cancérologue. Étude FIRE-3. Survie globale (RAS sauvage). Événements n/N (%). Médiane (mois). 1,0. IC 95. 91/171 (53,2 %). 33,1.

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Étude FIRE-3

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Tude fire 3

Étude FIRE-3

Résultats selon le statut RAS (KRAS/NRAS exons 2, 3, 4)

  • ESMO 2013 - D’après Stintzing S et al., LBA 17, actualisé

  • La Lettre du Cancérologue


Tude fire 31

Étude FIRE-3

Survie globale (RAS sauvage)

Événementsn/N (%)

Médiane(mois)

1,0

IC95

91/171

(53,2 %)

33,1

24,5-39,4

FOLFIRI + cétuximab

0,75

110/171

(64,3 %)

25,6

22,7-28,6

FOLFIRI + bévacizumab

HR = 0,70 ; IC95 : 0,53-0,92

p = 0,011

0,50

Probabilité de survie

Δ = 7,5 mois

0,25

0

0

12

24

36

48

60

72

Patients à risque (n)

  • La Lettre du Cancérologue

  • ESMO 2013 - D’après Stintzing S et al., LBA 17, actualisé

171

171

128

127

71

68

39

26

20

9

6

1


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