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OVEREATING STUDIES (individual subjects). Salans, L.B., et al. Journal of Clinical Investigation 50:1005-1011, 1971. OVEREATING STUDIES (individual subjects). Salans, L.B., et al. Journal of Clinical Investigation 50:1005-1011, 1971. OVEREATING STUDIES (individual subjects).

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slide1

OVEREATING STUDIES

(individual subjects)

Salans, L.B., et al. Journal of Clinical Investigation 50:1005-1011, 1971.

slide2

OVEREATING STUDIES

(individual subjects)

Salans, L.B., et al. Journal of Clinical Investigation 50:1005-1011, 1971.

slide3

OVEREATING STUDIES

(individual subjects)

Salans, L.B., et al. Journal of Clinical Investigation 50:1005-1011, 1971.

slide4

OVEREATING STUDIES

(individual subjects)

Salans, L.B., et al. Journal of Clinical Investigation 50:1005-1011, 1971.

slide5

OVEREATING STUDIES

(individual subjects)

Salans, L.B., et al. Journal of Clinical Investigation 50:1005-1011, 1971.

slide6

OVEREATING STUDIES

(individual subjects)

Salans, L.B., et al. Journal of Clinical Investigation 50:1005-1011, 1971.

slide7

Inflammation

Insulin Resistance

↓ NO

Insulin Resistance

↓ Fibrinolysis

Vasoconstriction

TNF α

Insulin

Resistance

IL-6

PAI-1

Resistin

Angiotensin

Insulin Resistance

Adiponectin

slide11

NUTRITION IN OBESITY

Percent Fat

Caloric Intake

slide12

OBESITY

Sedentary Pair Weighted

Sedentary Free Eaters

Exercise

Calories per Day

Oscai et al J Lipid Research 13:588-592, 1972.

slide13

OBESITY

Percent Fat (%)

Body Weight (g)

slide14

OBESITY

Fat Cell Number

Fat Cell Size

slide15

Changes in Lean & Fat Mass with Training - Men

Wilmore JH, Research Quarterly for Exercise and Sport 54:415-425, 1983.

slide16

Changes in Lean & Fat Mass with Training - Women

Wilmore JH, Research Quarterly for Exercise and Sport 54:415-425, 1983.

slide17

Total weight, fat mass & lean mass changes

with diet and exercise

Miller, WC et al International Journal of Obesity 21:941-947, 1997

slide18

Lean vs. Fat Mass Loss with Diet & Exercise

Fat

Weight Change (lbs)

Lean

Zuti & Golding, Physician & SportsMedicine 4:49-55, 1978

slide19

Lean vs. Fat Mass Loss In Overweight Adults

Lean

Fat

Weight Change (lbs)

Franklin, B., et al. Research Quarterly 1976.

slide20

SHORT vs. LONG BOUTS OF EXERICSE

Jakicic, et al. JAMA 282:1554-1560, 1999

slide21

ADHERENCE

Minutes per week

Jakicic, et al. JAMA 282:1554-1560, 1999

slide22

Weight Loss

Jakicic, et al. JAMA 282:1554-1560, 1999

slide23

Lifestyle Activity vs. Exercise is Weight Loss

Dunn, A.L. et al JAMA 281:327-334, 1999

slide24

MORBID OBESITY

Trend

No Wt Loss

Wt Loss

Reduce body fat in obese: Hill JO et al Physical Activity, Fitness, and Health: International Proceedings and Consensus statement, p 684-694, 1994.

slide25

PHYSICAL ACTIVITY & WEIGHT MAINTENANCE

Fogelholm, et al. Arch Int Medicine 160:2177-2184, 2000

slide26

N= 20 upper

N= 20 lower

  • UPPER:
  • Lost more on WHR
  • Lost only from Abd
  • Lost more weight

Walden et al, Am J Clin Nutr 47:229-234, 1988.

  • LOWER:
  • Lost Abd & Glut
slide27

OVEREATING STUDIES

(individual subjects)

Salans, L.B., et al. Journal of Clinical Investigation 50:1005-1011, 1971.

slide28

EXERCISE & THE FAT CELL

Tremblay, A., Int J Obesity 8:641-648, 1984.

slide29

Fitness & Fatness

Lee, C.D., et al. American Journal of Clinical Nutrition 69:373-380, 1999

slide30

EXERCISE & NUTRITION

Percent Body Fat (%)

Pitts, et al Am J Physiol 246:R495, 1984

slide31

EXERCISE & METABOLIC RATE

Poehlman, E.T., Med Sci Sports Exerc 21:515-525, 1989

slide32

EXERCISE & FOOD INTAKE

Neiman, D.C., J A, Dietetic Assoc 90: 1557-1562, 1990

slide33

Postprandial Lipemia and Exercise

Aldred, H.E, et al Metabolism 43:836-841, 1994

slide34

*

*

*

*

*

*

Baseline

1 year

*

slide35

Baseline

1 year

*interaction

slide36

Baseline

1 year

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