Quad rat vitals monitor
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Quad-Rat Vitals Monitor. Advisor: Paul Thompson Client: Dr. Alex Converse. Overview. PET Imaging Requirements Existing Devices Previous Semester’s Work Pulse Oximeter Probe Design Options LabVIEW Interface Design Options Where do we go from here? Acknowledgments. PET Imaging of Rats.

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Quad-Rat Vitals Monitor

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Quad rat vitals monitor

Quad-Rat Vitals Monitor

Advisor: Paul Thompson

Client: Dr. Alex Converse


Overview

Overview

  • PET Imaging

  • Requirements

  • Existing Devices

  • Previous Semester’s Work

  • Pulse Oximeter Probe Design Options

  • LabVIEW Interface Design Options

  • Where do we go from here?

  • Acknowledgments


Pet imaging of rats

PET Imaging of Rats

  • Positron emission tomography (PET) scans to monitor location of tracers in rats

  • Client scans four anesthetized rats at a time

    • Needs to monitor the rats’ vitals

http://homepages.cae.wisc.edu/~bme300/rat_monitor

_s09/reports/FinalPaperSpring09.pdf


Requirements quads vitals monitor

Requirements: Quads Vitals Monitor

  • Client needs to simultaneously monitor four rats

    • SpO2levels, accuracy of ±2%

    • Heart rates up to 500 beats per minute

    • Respiratory rates of 20 to 30 breaths per minute

    • Rectal temperatures of 93 - 100° F

  • Non-invasive probes and user-friendly interface


Existing devices

Existing Devices

  • Existing devices:

    • Client currently uses rudimentary devices to monitor vitals

    • Available: Pulse oximeter for mice and rats

      • Over $7000, one rat at a time

http://www.starrlifesciences.com/mri.html


Previous semester s work

Previous Semester’s Work

  • Developed circuit for detecting breathing rate using force sensing resistor

  • Designed and calibrated thermistor to detect temperature

  • Designed Graphical User Interface (GUI) in LabVIEW displaying breathing rate and temperature

  • Attempted to reverse engineer existing Pulse Oximeter

Force sensing resistor

LabVIEW interface


General probe requirements

General Probe Requirements

  • Applicable for rats of varying size

  • Reusable

  • Sufficient blocking of ambient light

  • Compatible LED and Photodiode

http://www.oximetry.org/pulseox/principles.htm


Foot clip

Foot Clip

  • Pros:

    • Similar to current device

    • Easy to reposition

    • Positioned far from the head

  • Cons:

    • Can displace easily

    • Risk of LED/Photodiode misalignment

    • Potential to apply excessive pressure


Foot wrap

Foot Wrap

  • Pros:

    • No displacement once attached

    • Alignment of LED/Photodiode maintained throughout testing

  • Cons:

    • Not adjustable

    • More involved cleaning process


Tail clip

Tail Clip

  • Pros:

    • Easy to attach

      • No confusion over placement location

    • Adjustable

  • Cons:

    • May interfere with catheter in tail

    • Potential to apply excessive pressure


Four corners with buttons

Four Corners with Buttons

Full display


Four corners with buttons1

Four Corners with Buttons

  • Pros:

    • Logical layout

    • Important information visible

  • Cons:

    • Extra clicking

    • History graphs incomparable

    • Less robust

A sample quarter of the final display


Tab interface

Tab Interface

  • Pros:

    • Uncluttered interface

    • Easy to program

  • Cons:

    • Inefficient

    • Data hard to compare

Full display


Four corners with histories

Four Corners with Histories

Full display


Four corners with histories1

Four Corners with Histories

  • Pros:

    • All data on one screen

    • Easy to compare trends

  • Cons:

    • Cluttered interface

    • Tiny on small screen

A sample quarter of the final display


Where do we go from here

Where do we go from here?

  • Finish LabVIEW GUI

    • Determine how data will be collected from Pulse Oximeter

  • Design pulse-ox probe to fit rat’s hind paw

    • Integrate with signal received from Graduate Students’ circuit

  • Print circuit boards

  • Fabricate housing apparatus


Acknowledgements

Acknowledgements

  • Professor Paul Thompson

  • Dr. Alex Converse

  • Amit Nimunkar

  • Tim Balgemann

  • Liz Ahlers

  • Nate Werbeckes


Questions

Questions?


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