Medicines and drugs. Analgesics. Analgesics – reduce pain. Pain. Pain is detected in the brain when nerve messages are sent from pain receptors in the body. The receptors are stimulated by chemicals (prostaglandins) released from cells that are damaged. Mild analgesics.
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Mild analgesics, such as aspirin,paracetamol (acetaminophen) and ibuprofen , function by stopping the transmission of pain from the source to the brain as they intercept the pain stimulus at the source.
They do this by interfering with the production of substances, such as prostaglandins, that are produced by injured tissues and that cause pain, swelling or fever.
These are all non-narcotics – do not interfere with the function of the brain
salicylic acid…. (caused vomiting)
A derivative = a new compound from changing another compound
To convert salicylic acid (2-hydroxybenzoic acid) into aspirin the hydrogen atom of the OH group is replaced by a COCH3 group to form an ester functional group which makes the compound less irritating to the stomach and easier to take.
All structures above are in the IB data booklet
Morphine + ethanoic acid Heroin and Water
Increase in effects: Codeine Morphine Heroin