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Chapter 12.10. Human Genetic Analysis. AP Biology Fall 2010. Chapter 12.10 Objectives. Explain how pedigree are constructed Distinguish between genetic abnormalities vs. genetic disorders. Human Genetic Analysis. Data on human inheritance is displayed in pedigrees.

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chapter 12 10

Chapter 12.10

Human Genetic Analysis

AP Biology

Fall 2010

chapter 12 10 objectives
Chapter 12.10 Objectives
  • Explain how pedigree are constructed
  • Distinguish between genetic abnormalities vs. genetic disorders
human genetic analysis
Human Genetic Analysis
  • Data on human inheritance is displayed in pedigrees
human genetic analysis1
Human Genetic Analysis
  • Human genetics is difficult to study
    • We live under variable conditions in diverse environments
    • Humans mate by chance, and may or may not choose to reproduce
    • Humans live as long as those that study them
    • The small family size characteristic of human beings is not sufficient for meaningful statistical analysis
human genetic analysis2
Human Genetic Analysis
  • A pedigree is a chart that shows genetic connections among individuals
    • The analysis of family pedigrees provides data on inheritance patterns through several generations
    • Knowledge of probability and Mendelian inheritance patterns is used in analysis of pedigrees to yield clues to a trait’s genetic basis
human genetic analysis3
Human Genetic Analysis
  • Some traits are deviations from the average
    • Genetic abnormality: term applied to a genetic condition that is a deviation from the usual, or average, and is not life-threatening
      • Person born with 6 digits on a hand
    • Genetic Disorder: is more appropriately used to describe conditions that cause medical problems
      • Cystic fibrosis
    • Syndrome: recognized set of symptoms that characterize a disorder
      • Abnormal glandular secretions, tissue, organ damage
review
Review
  • Can you read a pedigree chart?
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