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Responding To External Challenges and Opportunities:. Research at UPR at The Beginning of Its Second Century. Presented at NSF Caribbean Colloquium on Power Quality (CCPQ) 2003 Dr. Manuel Gómez Vice President for Research and Technology Dorado, PR June 25, 2003. [email protected]

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Responding to external challenges and opportunities

Responding To External Challenges

and Opportunities:

Research at UPR at The Beginning of Its Second Century

Presented at NSF Caribbean Colloquium on Power Quality

(CCPQ) 2003

Dr. Manuel Gómez

Vice President for Research and Technology

Dorado, PR

June 25, 2003

[email protected]

UPR: http://www.upr.clu.edu ; Central Administration: http://acosi.upr.clu.edu

EPSCoR: http://web.uprr.pr ; PR-LSAMP: http://shuttle.uprm.edu/prlsamp/bpc; Scientific Community: http://web.uprr.pr/wais


Location of the upr graduate campuses

An Issue of Scale

Puerto Rico at a Glance

Location of the UPRGraduate Campuses

Geography and

Demographics

Area: 3,434 square miles

(» Rhode Island’s)

Population: 3.8 M

(>25 states)

The Economy

K-12 Ed. System

Higher Education System

GDP: $48B

Exports: $23.9B

Manufacturing: 41% of GDP

S&T Industries: Pharmaceuticals

Electronics

Medical Devises

Service: 48% of GDP

Total Enrollment: 800,000

Public Enrollment: 620,000

(»L.A. Unified School Dist.)

Public Schools: 1,540

Enrollment in Higher Education: 170,000

(the sixth highest rate of enrollment in the world)

UPR System: 70,000

(41% of Higher Education Enrollment)

SMET Degrees Conferred

UPR: 2,000 (71%); Private Institution: 800 (29%)

UPR School of Engineering: 9th largest in the nation

2


The university of puerto rico as it enters its second century

The University of Puerto Ricoas it Enters its Second Century

3


Upr system at a glance

UPR System at a Glance

  • UPR was founded in 1983 and since its inception has conferred more than 300,000 degrees: UPR has educated most of the top leadership of the Island.

  • UPR is the premier Hispanic serving institution in the United States, with an enrollment of 70,000 students.

  • UPR is a multicampus system with 11 campuses: eight 4-year institutions and three graduate campuses. The graduate campuses are: UPR-Mayagüez, UPR-Río Piedras, and UPR-Medical Sciences.

  • UPR conferred 10,020 academic degrees in year 2002.

  • UPR graduate programs are developing very quickly: it conferred 100 PhD’s last year.

  • UPR offers 499 different degrees including 22 PhD programs.

  • UPR’s three graduate campuses aspire to become Research I Institutions, according to the Carnegie Classification. UPR-Río Piedras is already a Doctoral Research Intensive Institution, according to the Carnegie Classification.

  • UPR’s research activity, as measured by external funding, has grown exponentially since 1985, doubling every five years. For year 2001-2002, it received $62M in external funding for research.

  • UPR is member of INTERNET2; has teleconferencing facilities in every campus; its three graduate campuses are connected by OC-3 lines and a GigaPoP connects then to the mainland through an OC-3 line.

4


Responding to external challenges and opportunities

The Traditional University

Higher Education and

the Rest of the Educational Continuum

Undergraduate

Pre-College

Graduate

Human Resources

Human Resources

knowledge

knowledge

K - 12

13 - 16

16+ and PhD's

reform

reform

reform

Human

Resources;

knowledge

Technology Transfer;

Intellectual Property;

Human Resources

Human Resources

Economic Development

5


Responding to external challenges and opportunities

The Engaged University

The Seamless Continuum:

Strongly Coupled S&T Reform Process

Between Higher Education and

the Rest of the Educational Continuum

Undergraduate

Pre-College

Graduate

Human Resources

Human Resources

knowledge

knowledge

K - 12

13 - 16

16+ and PhD's

knowledge;

knowledge;

well prepared

quality faculty

reform

reform

reform

teachers

knowledge, strategic

knowledge

alliances;

Human

catalytic resources

Resources;

knowledge

catalytic resources

knowledge

catalytic

resources

Technology Transfer;

Intellectual Property;

Human Resources

Human Resources

Economic Development

S&T Policy for

State or Region

6


The university of puerto rico educates the next generation of the science and technology workforce

The University of Puerto RicoEducates the Next Generation of the Science and Technology Workforce

7


Responding to external challenges and opportunities

17,500

2,400

16,500

2,200

Enrollment

Degrees

15,500

2,000

14,500

1,800

13,500

1,600

12,500

1,400

Degrees confered per year

11,500

Total enrollment

1,200

10,500

9,500

1,000

85-86

86-87

87-88

88-89

89-90

90-91

91-92

92-93

93-94

94-95

95-96

96-97

97-98

98-99

99-00

00-01

90-91

91-92

92-93

93-94

94-95

95-96

96-97

97-98

98-99

99-00

00-01

Enrollment

Degrees

Total Enrollment in Science & Technology and

Bachelors in Science Degrees Conferred Per Year

for the University of Puerto Rico

Year

8


Responding to external challenges and opportunities

Date of Creation and Number of Degrees Conferred in the Natural Sciences and Engineering by Doctoral Program at UPR

9


Responding to external challenges and opportunities

Date of Creation and Number of Degrees Conferred in the Natural Sciences and Engineering by Doctoral Program at UPR (Cont.)

10


Responding to external challenges and opportunities

49

31

25

22

17

17

16

14

12

9

10

9

PhDs Conferred in Natural Sciences,

Medical Sciences, and Engineering at UPR

50

45

40

35

30

# Ph’sD Conferred

25

20

15

10

5

0

1990

1991

1992

1993

1994

1995

1996

1997

1998

1999

2000

2001

Academic Year

11


Responding to external challenges and opportunities

The University of Puerto RicoBecomes the First Research I University in Puerto Rico by Strengthening PhD Programs and Fostering Competitive Research in its Three Graduate Campuses

12


Responding to external challenges and opportunities

Developing Three Research I Campuses

At the University of Puerto Rico System

Present Level

Carnegie

Carnegie

Projected Level

of Activity

Classification

Classification

of Activity

2000

2005

(2005)

PhD

12

16

PhD

in five years

programs

programs

1) Río Piedras

Doctoral/Research

Doctoral/Research

60

90

PhD's

PhD's

Campus

University, Intensive

University, Extensive

per Year

per Year

$12M

$30M

in

in

R&D Funds

R&D Funds

in five years

5

5

PhD

PhD

Specialized

Specialized

programs

programs

Institution

Institution

2) Medical

[All Independent

[All Independent

PhD's

10

20

Sciences

PhD's

Medical Sciences

Medical Sciences

per Year

per Year

Campus

Campuses and

Campuses and

$19M

$40M

Medical Schools]

Medical Schools]

in

in

R&D Funds

R&D Funds

in five years

4

7

PhD

PhD

programs

programs

Masters

Doctoral/Research

3) Mayagüez

(Comprehensive)

University, Intensive

6

15

Campus

College or University

PhD's

PhD's

per Year

per Year

$13M

$35M

in

in

13

R&D Funds

R&D Funds


Responding to external challenges and opportunities

100

90

80

Public

70

Private

60

Expenditures ($ in Millions)

50

40

30

20

10

0

1972

1973

1974

1975

1976

1977

1978

1979

1980

1981

1982

1983

1984

1985

1986

1987

1988

1989

1990

1991

1992

1993

1994

1995

1996

1997

1998

1999

2000

Year

R&D Expenditures in Puerto Rico Universities

(NSF DATA)

14


Responding to external challenges and opportunities

$ 56.65 M

$ 23.46 M

Growth in UPR External Funds for R+D

1992-93 to 2001-02

$60

$55

$50

$45

External Fund for R&D (in millions)

$40

$35

$30

$25

$20

92-93

93-94

94-95

95-96

96-97

97-98

98-99

99-00

00-01

01-02

Academic Year

Net Growth in a 10 Year Period Resulted in 2.4 increase in available funds.

15


Responding to external challenges and opportunities

Publications in Peer Reviewed Science and Technology* Journals

of the University of Puerto Rico

(Information from the Science Citation Index**)

950

***

1000

900

800

700

510

600

500

313

400

# of Peer Reviewed Publications

228

300

154

200

100

0

85-86

92-93

98-99

04-05

2001-02

Year

# of researchers

At UPR

280

340

365

600

Publications

per Researcher

(0.6)

(0.7)

(0.9)

(1.5)

* Science and Technology: Includes Natural Sciences, Mathematics, Medicine, Agriculture and Engineering

** Source: "Science Citation Index"

*** The curve represents a 10% compounded growth rate

16


Responding to external challenges and opportunities

17


Responding to external challenges and opportunities

R&D IN SCIENCE & TECHNOLOGY FIELDS IS A TOP PRIORITY FOR UPR IN ORDER TO PROVIDE THE INFRASTRUCTURE FOR AN S&T DRIVEN ECONOMY FOR PUERTO RICO

  • The Government approved an S&T Policy in October, 1996. A strategic plan is being developed for its implementation.

  • The UPR Board of Trustees approved an S&T Policy in 1997 to channel resources and give priority to increase the number and quality of PhDs, intensify R&D activity, and promote the protection and commercialization of intellectual property in support of the Government's S&T Policy.

  • Since 1985 with funds from NSF, DOE, DOD, NASA, and EPA, the Experimental Program to Stimulate Competitive Research (EPSCoR) has accelerate the development of infrastructure and nurture competitive R&D in Puerto Rico. With an annual budget in excess of $12M, more than 150 researchers carry on cutting edge research in five thrust areas.

18


Responding to external challenges and opportunities

NSF EPSCoR

NASA

EPSCoR

DEPSCoR

DoE

EPSCoR

Development of target areas based on

existing capabilities, growth potential,

and contribution to the Island’s economy

PR-EPSCoR Thrust Areas Evolution

NIH

IDEA

NSF EPSCoR Phase IV

NSF EPSCoR Phase V

Integrative Biomolecular Processes

Biotechnology

Engineering Infrastructure

Environmental Research

Environmental Science and Engineering

Information Technology Research

High Performance Computing

Materials Science

Materials Science

External Peer Assessment

American Association for the Advancement of Science

NSF EPSCoR Phase V Funds: $13.5M

19


Engineering research centers initiative

Engineering Research Centers Initiative

20


A strategy to develop state of the art engineering research centers

A STRATEGY TO DEVELOP STATE-OF-THE ARTENGINEERING RESEARCH CENTERS

  • UPR is actively participating in three ERC’s

    • Center for Subsurface Sensing and Imaging Systems (CenSSIS)

      • An alliance with Rensselaer Polytechnic Institute, Northeastern University, and Boston University

      • Partnership with research hospital and marine stations

      • Research in remote sensing of biological systems, submarine exploration and subsoil sensing

      • Development of test-beds to develop new remote sensing technologies

      • Partnership with industries

21


A strategy to develop state of the art engineering research centers cont

A STRATEGY TO DEVELOP STATE-OF-THE ARTENGINEERING RESEARCH CENTERS (Cont.)

  • Center for Collaborative Adaptive Sensing of the Atmosphere (CASA)

    • Collaboration with University of Massachusetts, University of Oklahoma, and Colorado State University

    • Industrial partners: Hewlett Packard and Verizon

    • Radar network for detection of every day and extreme meteorological events

    • Integration of information on extreme meteorological events with the needs of emergency management agencies and the public

22


Responding to external challenges and opportunities

CENTER FOR POWER ELECTRONICS SYSTEMS


Electric energy processing system laboratory e 2 psyl

Electric Energy Processing System Laboratory (E2PSyL)

  • Three main areas:

    • component testing and prototyping

    • component modeling and simulation

    • power quality and energy conversion

  • Multi-disciplinary projects

    • Industrial and Mechanical Engineering (CPES)

  • NSF and UPRM funds (over $350k)

    • Dr. Vélez-Reyes PECASE award 1997

    • Dr. Efraín O’Neill NSF MRI Award 2001

24


Acquisition of instrumentation for the electric energy processing systems laboratory at uprm

Acquisition of Instrumentation for the Electric Energy Processing Systems Laboratory at UPRM

NSF Major Research Instrumentation Grant (MRI)

Dr. Efraín O’Neill-Carrillo, PI

Dr. Miguel Vélez-Reyes, Co-PI

Dr. Lionel Orama-Exclusa, Co-PI

Dr. Agustín Irizarry-Rivera, Co-PI

Dr. José R. Cedeño-Maldonado, Co-PI

25


Research infrastructure

Research Infrastructure

  • Enhancement of research capabilities at E2PSyL

  • Power electronics

  • Electric drives

  • Power quality

  • Transient studies

  • Improved computational capabilities

26


Biotechnology initiative

Biotechnology Initiative

27


Responding to external challenges and opportunities

Federal EPSCoR Funding (1990-2003)

450

400

350

300

NSF

250

DOE

$$ (in millions)

USDA

200

NIH

DoD

150

NASA

100

EPA

DOC

50

Total

0

FY90

FY91

FY92

FY93

FY94

FY95

FY96

FY97

FY98

FY99

FY00

FY01

FY02

FY03

Fiscal Year

projected

28


Responding to external challenges and opportunities

The University of Puerto RicoImplements a Multicampus a Strategy to Develop its R&D Capacity in Biotechnology using NIH Funds

29


Responding to external challenges and opportunities

Biotechnological

and Pharmaceutical

Industries

The Biotechnology Trilogy

2001

COBRE I

Center for Molecular,

Developmental and

Behavioral Science

COBRE II

BRIN

Center for Research

in Protein Structure,

Function and Dynamics

Biomedical Research;

Bioinformatics Infrastructure

Network

NIH Funds: $24.5M

UPR Matched Funds: $6.5M

30


Responding to external challenges and opportunities

University of Puerto Rico

Center for Molecular, Developmental and Behavioral Neuroscience

COBRE I

31


Responding to external challenges and opportunities

University of Puerto Rico

COBRE

Center for Molecular, Developmental and Behavioral Neuroscience

  • Projects:

    • Molecular mechanism of brain injury: P2Y2 nucleotide receptor in ischemia. Fernando A. González, Ph.D.

    • Emotional memory: Genomic basis of emotional learning and memory. Sandra Peña, Ph.D.

    • Cocaine-seeking behavior: Neural and molecular mechanisms in striatal learning. Carmen Maldonado, Ph.D.

    • Development of maternal behavior: Neurosteroid effects on the structure and function of a sexually dimorphic mammalian brain network. Juan C. Jorge, Ph.D.

32


Nih cobre ii program

NIH-COBRE II Program

UPR- Protein Research Center

33


Responding to external challenges and opportunities

UPR- Protein Research Center

Center for Research in Protein Structure, Function and Dynamics

Sponsored by the National Institutes of Health-Centers of Biomedical Research Excellence (NIH-COBRE II) Program

NIH Funding Period: Oct. 2001- Sept 2006

($8 Million / 5 years)

34


Responding to external challenges and opportunities

CURRENT PROJECTS & PI’s

  • Protein Structure, Dynamics, and Function.

    Dr. Juan López Garriga - Chemistry UPR-Mayagüez

    Dr. Carmen Cadilla– Biochemistry-UPR-Medical Sciences

    • Aimed at understanding the reactions between hemoglobin (Hb), myoglobin (Mb), and other heme proteins with H2O2.

  • Protein Interactions and Oligomerization.

    Dr. Belinda Pastrana - Ríos - Chemistry UPR-Mayagüez

    Dr. Elsa M. Cora – Biochemistry-UPR-Medical Sciences

    • Aimed at studying serum 110 kD-sEGFR, a circulating serum biomarker for epithelial ovarian cancer (EOC), a protein generated by alternative splicing of the EGFR message.

  • Protein Stability and Delivery.

    Dr. Kai Griebenow - Chemistry- UPR-Río Piedras.

    Dr. Reinhard Schweitzer-Stenner - Chemistry- UPR-Río Piedras.

    • Aimed at studies on the improvement of the controlled delivery of proteins from biocompatible poly(lactide-co-glycolide) (PLG) by increasing their lifetime

35


Biomedical research infrastructure networks in puerto rico brin pr

Biomedical Research Infrastructure Networks in Puerto Rico (BRIN-PR)

Dr. Fernando A. González, P.I.

Institutional Development Award (IDeA)

36


Brin purpose

BRIN Purpose

  • …to establish Biomedical Research Infrastructure Networks (BRIN) to further enhance the research capacity of institutions through collaborative partnerships.

37


Brin organization

BRIN Organization

38


Responding to external challenges and opportunities

COBRE I

Center for Molecular, Developmental and Behavioral Neuroscience

COBRE II

Center for Research in Protein Structure, Function and Dynamics

COBRE III

Center for Clinical Proteomics

(Submitted)

BRIN

Bioinformatics

HPCf

COBRE IV

Microarray Analysis

(Planned)

Using NIH Funds to Expand UPR Biotechnology R+D Initiative

by Creating New Research Programs

Approved Funds $30.5M

Expected New NIH Funds $20M

39


Cobre iv center for bioinformatics

COBRE IVCenter for Bioinformatics

  • Brings Mathematicians, Statisticians, Bioinformaticians, Biologist and Chemical Engineer in a Multidisciplinary/Multicampus Team to study and model microarrays.

  • Will develop the following microarray areas:

    • Simulation and reverse engineering problem of genetic networks.

    • Gene network design and error correction for microarrays

    • Microarray expression analysis: statistical significance of expression changes

    • Microarray data analysis

  • Will also develop the following Bioinformatic thrusts:

    • Pattern recognition in tandem mass spectrometry.

    • Statistical significance of multiple sequences alignment and gapped local alignments.

  • Proposed Five Year Budget: $10M(NIH + UPR)

40


Academic industry partnership for innovation

Academic/Industry Partnershipfor Innovation

41


Responding to external challenges and opportunities

The NSF Partnerships for Innovation (PFI)

Puerto Rico received a PFI to accelerate the Innovation Process (February, 2001):

Mission of the PFI

DevelopIdeation to Commercialization pathways to achieve innovation

The PFI is an Alliance of:

Academia:

University of Puerto Rico

Polytechnic University

Inter American University

Business:

P.R. Chamber of Commerce

P.R. Manufacturer’s Association

Advent Morro Equity Partners (Venture Capital)

MOVA Pharmaceutical

INDUNIV

Virtual, Inc. (Commercial Incubator)

Government:

Federal Small Business Administration

P.R. Department of Economic Development and Commerce

42


Responding to external challenges and opportunities

Goals and Objectives of PFI

Goal

Create a continuous pipeline for innovation: fromideation to commercialization. 

Objectives

A. Develop Entrepreneurial skills and nurture an innovation competent workforce.

  • Incorporate curricular materials on the nature of technology and innovation in the K-12 curriculum.

  • Entrepreneurship development program for undergraduates.

  • Develop new Ph.D.’s of relevance to innovation

    • Materials Science

    • Computational Sciences & Engineering

    • Medical Biotechnology

43


Responding to external challenges and opportunities

Goals and Objectives of PFI (cont.)

  • Improve Access to New Knowledge to Drive the Innovation Process

    • PFI – Web-based Interactive S&T Resources Data base

    • Create an Enterprise Forum

    • Provide Assistance for the Preparation of SBIR/STTR

    • Open UPR Intellectual Property and Technology Commercialization Office (IPTC) to Entrepreneurs & Start-Ups Companies.

  • Create Infrastructure to Enable Innovation

    • Promote and support the formation of a system of incubators

    • Create R&D institutes to promote innovation

  • Advocacy and Promoting Systemic Thinking in the Development of S&T Innovation in Puerto Rico: Implementing the S&T Policy

44


Responding to external challenges and opportunities

Building a High Performance Computing andINTERNET2 Informatics Infrastructurefor Research and Education

45


High performance computing facility

High Performance Computing Facility

  • The High Performance Computing Facility was created in 1998, with NSF funding, to serve the computational needs of the research community; it provides:

    • Center for Numerical Supercomputing.

    • Bioinformatics Resource Center.

    • Two visualization laboratories.

    • Access Grid Video Conferencing Center.

    • Serves Puerto Rico’s Internet2 Services Alliance (PRISA net) GigaPoP.

  • Computing Facilities

    • Silicon Graphics Origin 300 32 MIPS 14000 Processors.

    • Silicon Graphics Origin 2400/Onyx 2 24 MIPS Processors.

    • Silicon Graphics Origin 2000 desk side cluster 16 MIPS desk side cluster.

    • Linux Supercluster 156 processors.

46


Responding to external challenges and opportunities

Puerto Rico Internet 2 Services Association

PRISA net

Other Internet 2

Institutions

National

National

Research Labs

Supercomputing

facilities

RCM

International

Research

OC-3

Facilities

OC-3 = 155Mb/sec

RRP

Abilene

OC-3 = 100xT1

OC-3

Centennial

ATM Cloud

OC-3

(Fiber optics)

AO

OC-3

OC-3

FIU GigaPOP

ATM =

OC-3

Asynchronous

OC-3 (Quest on

America II)

Transfer Mode

RUM

OC-3

OC-3

Centennial

OC-3

ATM

PRISA GigaPOP

PRISA will entertain alliances and partnerships on research and educational

projects with industry and C of C members in Puerto Rico

47


Www hpcf upr edu prstp

www.hpcf.upr.edu/prstp

48


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