ศริศักดิ์ สุนทรไชย สาขาวิชาวิทยาศาสตร์สุขภาพ มหาวิทยาลัยสุโขทัยธรรมาธิราช

1. Globally Harmonized System of Classification System of Classification and Labelling of Chemicals (GHS)Hazard Communication :Labelling and SDS ศริศักดิ์ สุนทรไชย สาขาวิชาวิทยาศาสตร์สุขภาพ มหาวิทยาลัยสุโขทัยธรรมาธิราช

2. One of the objectives of the work on the Globally Harmonized System (GHS) is the development of aharmonized communication system, including Labelling, Safety data sheets (SDS) and easily understandable symbols, based on classification criteria developed for the GHS.

3. Hazard Communication In The GHS Document • Ch. 1.4,Hazard Communication: Labelling • Target audiences • comprehensibility • translation • standardization • supplemental information • updating • confidential business information • training

4. Labelling : Target audiences Labels communicate the hazard(s) according GHS classification to target audiences -Workplace - Consumers - Emergency responders - Transport

5. Labelling : Target audiences (1) • Workplace Employers and workers need to know the hazards specific to the chemicals used and or handled in the workplace, as well as information about the specific protective measures required to avoid the adverse effects that might be caused by those hazards.

6. Labelling : Target audiences (2) - Consumers The label in most cases is likely to be the sole source of information readily available to the consumer. The label, therefore, will need to be sufficiently detailed and relevant to the use of the product.

7. Labelling : Target audiences (3) - Emergency responders Emergency responders need information on a range of levels. To facilitate immediate responses, they need accurate, detailed and sufficiently clear information. This applies in the event of an accident during transportation, in storage facilities or at workplaces.

8. Labelling : Target audiences (4) -Transport The UN Recommendations on the Transport of Dangerous Goods, Model regulations, cater for a wide range of target audiences although transport workers and emergency responders are the principal ones. Others include employers, those who offer or accept dangerous goods for transport or load or unload packages of dangerous goods into or from transport vehicles, or freight containers.

9. Target audiences Needs • Workplace including pesticides and pharmaceuticals • Labels and Safety data sheets • Consumers • Labels • Transport • Labels, Placards, Transport documents (TREM Card) • Emergency responders • Labels, Placards

10. Label Elements • Pictograms • Signal Words • Hazard Statements • Precautionary statements • Product Identifier • Supplier Identification • Supplemental Information

11. GHS Pictogram UN RTDG Pictogram Labelling • Pictograms Pictogram for flammable liquid in the UN Model Regulations (Symbol: Flame: Black or White background.) Pictograms prescribed by the GHS should have a black symbol on a white background with a red frame sufficiently wide to be clearly visible.

12. LabellingPictograms: Convey health, physical & environmental hazard information.

13. GHS Pictograms

14. UN Dangerous Goods Transport Labelling

15. Labelling • Signal Words: “Danger”or“Warning” are used to emphasis hazard and indicate the relative of severity of the hazard.

16. Labelling • Hazard Statements: Standard phrased assigned to a hazard class and category to specified the nature of the hazard. Example : Acute Toxicity Oral　； • category 1 “Fatal if swallowed “ • Category 2 “Fatal if swallowed ” • Category 3 “Toxic if swallowed” • Category 4 “Harmful if swallowed” • Category 5 “Maybe harmful if swallowed”

17. Label elements　：　Example １　（Acute toxicity, oral) (GHS Recommendation Annex １) Pictograms Signal word Hazard statements

18. Label elements　：　Example ２　（Carcinogenicity) (GHS Recommendation Annex １)

19. Label elements：Example 3　（Aquatic toxicity, acute)(GHS Recommendation Annex １)

20. Labellining • Precautionary Statements GHS label should include appropriate precautionary information GHS document contains examples of precautionary statements which can be used The intent is to harmonize precautionary statements in the futureas Annex 3 to “Purple book”

21. Labelling • Precautionary statements: Measures to minimize or prevent adverse effects. Example : (GHS Recommendation Annex 3) A3.3.3.3Accident caused by ingestion －If swallowed, seek medical advice immediately and show this container or label. －If swallowed, rinse mouth with water (only if the person is conscious). －If swallowed, and the victim is conscious and alert, induce vomiting immediately, as directed by medical personnel.

22. GHS Annex 3 “Precautionary Statements (PS)” ACUTE TOXICITY - ORAL （CHAPTER 3.1)Hazard Category Signal Word Hazard Statement1Danger Fatal if swallowed 2Danger Fatal if swallowed Symbol Skull and crossbones

23. Labelling • Product Identifier Name or number used for a hazardous product on a label or in the SDS. Unique means by which the substance or mixture can be identified within the particular use setting UN proper shipping name also to be used on the package when substance or mixture covered by the UN RTDG

24. Labelling • Supplier Identification: The name, address and telephone should be provided on the label. • Supplemental Information: non-harmonized information.

25. Label example

26. Precedence for the allocation of symbols (1) For substances and mixtures covered bythe UN Recommendations on the Transport of Dangerous Goods, Model Regulations,the precedence of symbols for physical hazards should follow the rules ofthe UN Model Regulations.

27. Precedence for the allocation of symbols (2) For health hazards the following principles ofprecedence apply: (a) if theSkull and crossbonesapplies, theExclamation markshould not appear; (b) if theCorrosive symbolapplies, theExclamation markshould not appear where it is used for skin or eye irritation; (c) if theHealth hazard symbolappears for respiratory sensitisation, theExclamation markshould not appear where it is used for skin sensitisation or for skin or eye irritation.

28. Precedence for the allocation of symbols (3) Precedence for allocation of signal words If the signal word‘Danger’applies, the signal word‘Warning’should not appear.

29. Precedence for the allocation of symbols 　 ＞ 　　 ＞ Skin / Eye irritation Respiratory＞ Skin sensitization, sensitization Skin / Eye irritation DANGER ＞ WARNING

30. Proposed GHS Classification for Global hazexyl systemol Flammable liquid : Category 4 (No symbol, Warning, Combustible liquid) Acute oral toxicity : Category 4 (Symbol: ! , Warning, Harmful if swallowed) Acute dermal Toxicity : Category 3 (Symbol: skull and crossbones, Danger, Toxic in contact with skin) Skin corrosion/irritation: Category 1C (Symbol: corrosion, Danger, Cause severe skin burns and eye damage) Eye damage/irritation : Category 2B (No symbol, Warning, Causes eye irritation)

31. Proposed GHS Classification for Global hazexyl systemol Symbols Flammable liquid : Category 4 (No symbol, Warning, Combustible liquid) Acute oral toxicity : Category 4 (Symbol: !, Warning, Harmful if swallowed) Acute dermal Toxicity : Category 3 (Symbol: skull and crossbones, Danger, Toxic in contact with skin) Skin corrosion/irritation: Category 1C (Symbol: corrosion, Danger, Cause severe skin burns and eye damage) Eye damage/irritation : Category 2B (No symbol, Warning, Causes eye irritation)

32. Proposed GHS Classification for Global hazexyl systemol Signal word Flammable liquid : Category 4 (No symbol, Warning, Combustible liquid) Acute oral toxicity : Category 4 (Symbol: ! , Warning, Harmful if swallowed) Acute dermal Toxicity : Category 3 (Symbol: skull and crossbones, Danger, Toxic in contact with skin) Skin corrosion/irritation: Category 1C (Symbol: corrosion, Danger, Cause severe skin burns and eye damage) Eye damage/irritation : Category 2B (No symbol, Warning, Causes eye irritation)

33. Proposed GHS Classification for Global hazexyl systemol Hazard Statements Flammable liquid : Category 4 (No symbol, Warning, Combustible liquid) Acute oral toxicity : Category 4 (Symbol: ! , Warning, Harmful if swallowed) Acute dermal Toxicity : Category 3 (Symbol: skull and crossbones, Danger, Toxic in contact with skin) Skin corrosion/irritation: Category 1C (Symbol: corrosion, Danger, Cause severe skin burns and eye damage) Eye damage/irritation : Category 2B (No symbol, Warning, Causes eye irritation)

34. GHS Label Global Hazexyl Systemol Globalethylene (2-Hazanol） CAS No. 222-22-2 Product identifier Pictograms Danger Hazard statements ・Combustible liquid ・Harmful if swallowed ・Toxic in contact with skin ・Cause serious skin burns and eye irritation Signal word Hazard statements Supplier: United Nations Corp. Ltd. 1-1, Peace Ave. Geneva, Switzerland TEL: 41 22 917 00 000 FAX: 41 22 917 00 000 Supplier identification

37. GHSHazard Communication :Safety Data Sheet (SDS)

38. Role of the SDS in the GHS SDS should provide comprehensive information about a chemical substance or mixture for use in workplace. Both employers and workers use it as a source of information abouthazards, and to obtain advice on safety precautions.

39. ＳＤＳ Target audiences • Workplace • Consumers • Emergency responders • Transporters – TREM CARD

40. When is a SDS required? SDS should be produced for all substances and mixtures which meet the harmonized criteria under the GHS and for all mixtures which contain substances that meet the GHS criteria exceeding the cut-off limits for each hazard class.

41. Cut-off values/Concentration limits for each health and environmental hazard class

42. Safety Data Sheets • Primarily workplace use 16 heading format agreed, similar to the ILO and ISO format, but sections 2 and 3 reversed • Minimum additional information specified, where applicableor available, under the relevant headings

43. SDS format (1) 1.Identification 2. Hazard(s) identification 3. Composition/information on ingredients 4.First-aid measures 5. Fire-fighting measures 6. Accidental release measures 7. Handling and storage 8. Exposure controls/personal protection

44. SDS format (2) 9. Physical and chemical properties 10. Stability and reactivity 11. Toxicological information 12. Ecological information 13. Disposal considerations 14. Transport information 15. Regulatory information 16. Other information.

45. Minimum information for an SDS ingredients (1)

46. Minimum information for an SDS ingredients (2)

47. Minimum information for an SDS ingredients (3)

48. Minimum information for an SDS ingredients (4)

49. Minimum information for an SDS ingredients (5)

50. Minimum information for an SDS ingredients (6)